DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kr-h1 and ZBTB16

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_001018011.1 Gene:ZBTB16 / 7704 HGNCID:12930 Length:673 Species:Homo sapiens


Alignment Length:475 Identity:127/475 - (26%)
Similarity:184/475 - (38%) Gaps:88/475 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 TELLDISKSPAK----------------AVAVKKSPAKDSATTKMVYYSANQLLIKTEQSSQAQF 75
            ||::.:.:.|::                .|..:......:.|...|..||.:|....|:|::   
Human   243 TEMMQVDEVPSQDSPGAAESSISGGMGDKVEERGKEGPGTPTRSSVITSARELHYGREESAE--- 304

  Fly    76 CLQVPPPLTATTTSVGLGVPPSGGQQEHFELLQTPQQRQMQLQLQDQHQQEQQQFVSYQLAIQQH 140
              |||||..|.....|....|:...::|..:..                           .:..|
Human   305 --QVPPPAEAGQAPTGRPEHPAPPPEKHLGIYS---------------------------VLPNH 340

  Fly   141 QKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQV----------RKPSASKPQFK 195
            :.........|:|:........|..:.....||......:..::          .|..:.....:
Human   341 KADAVLSMPSSVTSGLHVQPALAVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQ 405

  Fly   196 CDQCGMTFGSKSAHTSHTKSHS--KNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTI 258
            |..||:......|...|.|.||  |.....|.|..             .|:...|.:.:      
Human   406 CSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKR-------------FLDSLRLRMHL------ 451

  Fly   259 KPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTG-ERPFECEFCHKLFSVKENLQVHRRIHT 322
              ||: :|||..:.|:.|...|:....|..|.:|||| :....|..|.|.|..:..||.|..:|.
Human   452 --LAH-SAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHA 513

  Fly   323 KERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPE 387
            ..|.|.|..|.|.|.....|.||:|.|||:.|::|..|...|.....|..|.|.|||||||:|  
Human   514 GVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYEC-- 576

  Fly   388 PGCGKGFTCSKQLKVHSRTHTGEKPYHCDICF-RDFGYNHVLKLHRVQHYGSKCYKCTICDETFK 451
            .||||.|:...||:.|.|.||||||:.|.:|. |...|:.::| |...|.|:..|:||||.|...
Human   577 NGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIK-HLRTHNGASPYQCTICTEYCP 640

  Fly   452 NKKEMEAHIKGH-ANEVPDD 470
            :...|:.|:||| ..|:|.|
Human   641 SLSSMQKHMKGHKPEEIPPD 660

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 6/19 (32%)
COG5048 <270..420 CDD:227381 62/151 (41%)
zf-C2H2 271..293 CDD:278523 5/21 (24%)
C2H2 Zn finger 273..293 CDD:275368 5/19 (26%)
zf-H2C2_2 286..309 CDD:290200 9/23 (39%)
C2H2 Zn finger 301..321 CDD:275368 7/19 (37%)
zf-H2C2_2 313..338 CDD:290200 10/24 (42%)
C2H2 Zn finger 329..349 CDD:275368 8/19 (42%)
zf-H2C2_2 344..366 CDD:290200 10/21 (48%)
C2H2 Zn finger 357..377 CDD:275368 6/19 (32%)
zf-H2C2_2 370..396 CDD:290200 16/25 (64%)
C2H2 Zn finger 385..407 CDD:275368 10/21 (48%)
zf-H2C2_2 400..424 CDD:290200 12/24 (50%)
C2H2 Zn finger 415..435 CDD:275368 6/20 (30%)
zf-C2H2 441..463 CDD:278523 9/21 (43%)
C2H2 Zn finger 443..463 CDD:275368 8/19 (42%)
ZBTB16NP_001018011.1 BTB 25..125 CDD:306997
Herpes_ICP4_C 177..>327 CDD:332854 19/88 (22%)
Interaction with RUNX1T1. /evidence=ECO:0000269|PubMed:10688654 200..300 9/56 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 215..236
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..332 18/87 (21%)
C2H2 Zn finger 406..426 CDD:275368 6/19 (32%)
C2H2 Zn finger 434..454 CDD:275368 5/40 (13%)
COG5048 <448..622 CDD:227381 71/185 (38%)
C2H2 Zn finger 463..483 CDD:275368 5/19 (26%)
C2H2 Zn finger 492..512 CDD:275368 7/19 (37%)
C2H2 Zn finger 520..540 CDD:275368 8/19 (42%)
C2H2 Zn finger 548..568 CDD:275368 6/19 (32%)
C2H2 Zn finger 576..596 CDD:275368 10/21 (48%)
C2H2 Zn finger 604..624 CDD:275368 6/20 (30%)
C2H2 Zn finger 632..652 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.