Protein Alignment Kr-h1 and ZNF91

DIOPT Version :10

• Sequence 1: NP_477466.1
• Gene: Kr-h1 / 33861
• FlyBaseID: FBgn0266450
• Length: 845
• Species: Drosophila melanogaster
• Sequence 2: NP_003421.2
• Gene: ZNF91 / 7644
• HGNCID: 13166
• Length: 1191
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 113/318 - (35%)
• Similarity: 147/318 - (46%)
• Gaps: 53/318 - (16%)

  Fly   167 KTEPVG-GFPASAAVVSQVRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNGASGA 230
            |.|..| .|..|:|:....|..:..|| :||.:||..|.:.|...:|..:|::.:
Human   631 KCEECGKAFSHSSALAKHKRIHTGEKP-YKCKECGKAFSNSSTLANHKITHTEEK---------- 684

  Fly   231 GVAAPVSTAAIELNDAGLPVGIPKSPTIKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTG 295
                                                   ||:|..|.|||...:.|.:|...|.|
Human   685 ---------------------------------------PYKCKECDKTFKRLSTLTKHKIIHAG 710

  Fly   296 ERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVC 360
            |:.::||.|.|.|:...||.:|:.|||.|:||||:.||:||..|..|.:|.||||.|:|.||..|
Human   711 EKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKEC 775

  Fly   361 EKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYN 425
            .|.||.|..|..|.|.|||||||||.|  |||.|:.|..|..|...|||||||.|..|.:.|.::
Human   776 GKAFIWSSTLTRHKRIHTGEKPYKCEE--CGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHS 838

  Fly   426 HVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIKGHANEVPDDEAEAAAASAAAST 483
            ..|..|::.|.|.|.|||..|.:.|.....:..|...|..|.|....|...|...:||
Human   839 SALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSST 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		COG5048	<270..420	CDD:227381	77/149 (52%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
		C2H2 Zn finger	329..349	CDD:275368	9/19 (47%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		C2H2 Zn finger	385..407	CDD:275368	9/21 (43%)
		C2H2 Zn finger	415..435	CDD:275368	5/19 (26%)
		zf-C2H2	441..463	CDD:395048	6/21 (29%)
		C2H2 Zn finger	443..463	CDD:275368	4/19 (21%)
ZNF91	NP_003421.2	KRAB	13..73	CDD:214630
		C2H2 Zn finger	155..176	CDD:275368
		C2H2 Zn finger	212..232	CDD:275368
		C2H2 Zn finger	240..260	CDD:275368
		C2H2 Zn finger	268..288	CDD:275368
		zf-H2C2_2	281..305	CDD:463886
		C2H2 Zn finger	296..316	CDD:275368
		COG5048	320..708	CDD:227381	26/126 (21%)
		C2H2 Zn finger	324..344	CDD:275368
		C2H2 Zn finger	352..372	CDD:275368
		C2H2 Zn finger	380..400	CDD:275368
		C2H2 Zn finger	408..428	CDD:275368
		C2H2 Zn finger	436..456	CDD:275368
		C2H2 Zn finger	464..484	CDD:275368
		C2H2 Zn finger	492..512	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	548..568	CDD:275368
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		COG5048	628..1069	CDD:227381	113/318 (36%)
		C2H2 Zn finger	632..652	CDD:275368	6/19 (32%)
		C2H2 Zn finger	660..680	CDD:275368	6/19 (32%)
		C2H2 Zn finger	688..708	CDD:275368	7/19 (37%)
		C2H2 Zn finger	716..736	CDD:275368	8/19 (42%)
		C2H2 Zn finger	744..764	CDD:275368	9/19 (47%)
		C2H2 Zn finger	772..792	CDD:275368	9/19 (47%)
		C2H2 Zn finger	800..820	CDD:275368	9/21 (43%)
		C2H2 Zn finger	828..848	CDD:275368	5/19 (26%)
		C2H2 Zn finger	856..876	CDD:275368	4/19 (21%)
		C2H2 Zn finger	885..904	CDD:275368	4/12 (33%)
		C2H2 Zn finger	912..932	CDD:275368
		C2H2 Zn finger	940..960	CDD:275368
		C2H2 Zn finger	968..988	CDD:275368
		C2H2 Zn finger	996..1016	CDD:275368
		C2H2 Zn finger	1024..1044	CDD:275368
		C2H2 Zn finger	1052..1072	CDD:275368
		SFP1	<1075..1154	CDD:227516
		C2H2 Zn finger	1080..1100	CDD:275368
		C2H2 Zn finger	1108..1128	CDD:275368
		C2H2 Zn finger	1136..1156	CDD:275368