DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr-h1 and Zscan25

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:XP_038945553.1 Gene:Zscan25 / 363872 RGDID:1308619 Length:554 Species:Rattus norvegicus


Alignment Length:498 Identity:143/498 - (28%)
Similarity:201/498 - (40%) Gaps:82/498 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 PKQI--WIKDVLKKSGTELLD-----ISKSPAKAVAVKKSPAKDSATTKMVYYSANQLLIKTEQS 70
            |:::  ||::....||..|:.     :..:.||||..|:.    |....:..::..:.|:.....
  Rat    95 PRELYTWIREHSPDSGKALVAMVEELMGSTEAKAVGEKRV----SRPFSVPCHAQGEQLVTALGG 155

  Fly    71 SQAQFCLQVPPPLTATTTSVGLGVPPSGG--QQEHFELLQTPQQRQMQLQLQDQHQQEQQQFVSY 133
            ...|..:.:.|          :.|.|..|  |.|..:.|......|:.....|..|..|:|    
  Rat   156 GSWQSGIHLGP----------VEVKPEWGIPQGEGVQSLGPSTAEQLSQGPGDGTQAFQEQ---- 206

  Fly   134 QLAIQQHQKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQVRKP----------- 187
            .|.|..            :.:..||.:...|.|    ..||   .|..||...|           
  Rat   207 ALPILH------------VGSGLPTVSARDQEI----AAGF---LAATSQGLGPFKDMTLGFPEE 252

  Fly   188 ---SASKPQFKC-------DQCGMT--FGSKSAHTSHTKSHSKNQ--DLSLNGASGAGVAAPVST 238
               ..:..|..|       ..||..  .|||.......:...|..  .|:.:|...|.:..||..
  Rat   253 EWRHVAPAQIDCFGEYVDSQDCGAPPGAGSKEKEAKPQQEDLKRAFVGLTSDGFGEAAIQVPVPG 317

  Fly   239 AAIELNDAGLPVGIPKSPTIKP-------LANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGE 296
            ...|....|....:|..|..:|       |:..::...|:||..|.|.|:..:.|:||.|||..|
  Rat   318 GTCEQEPGGSGTSVPGLPAPQPGVPLPEALSAHSSFWKPFQCPECGKGFSRSSNLVRHQRTHEEE 382

  Fly   297 RPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCE 361
            :.|.|..|.|.|:::|.|..|:|.|..:|||.|..|.:.|.....|..|.|.||||:|:||:.|.
  Rat   383 KAFGCVECGKGFTLREYLTKHQRTHLGKRPYVCGECWKTFSQRHHLEVHQRSHTGEKPYKCADCW 447

  Fly   362 KTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNH 426
            |.|.:...|::|.|||||||||.|.   |||.|:.:..|.||.|.|||||||.|.:|.:.|....
  Rat   448 KGFSRRQHLLVHRRTHTGEKPYTCE---CGKSFSRNANLAVHRRAHTGEKPYGCQVCGKRFSKGE 509

  Fly   427 VLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIK-GHANEVP 468
            .|..|:..|.|.|.|.|..|..:|..:..:..|.| .|..|.|
  Rat   510 RLVRHQRIHTGEKPYHCPACGRSFNQRSILNRHQKTQHRQEPP 552

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 6/28 (21%)
COG5048 <270..420 CDD:227381 71/149 (48%)
zf-C2H2 271..293 CDD:278523 9/21 (43%)
C2H2 Zn finger 273..293 CDD:275368 8/19 (42%)
zf-H2C2_2 286..309 CDD:290200 11/22 (50%)
C2H2 Zn finger 301..321 CDD:275368 8/19 (42%)
zf-H2C2_2 313..338 CDD:290200 10/24 (42%)
C2H2 Zn finger 329..349 CDD:275368 6/19 (32%)
zf-H2C2_2 344..366 CDD:290200 12/21 (57%)
C2H2 Zn finger 357..377 CDD:275368 7/19 (37%)
zf-H2C2_2 370..396 CDD:290200 16/25 (64%)
C2H2 Zn finger 385..407 CDD:275368 9/21 (43%)
zf-H2C2_2 400..424 CDD:290200 14/23 (61%)
C2H2 Zn finger 415..435 CDD:275368 5/19 (26%)
zf-C2H2 441..463 CDD:278523 6/22 (27%)
C2H2 Zn finger 443..463 CDD:275368 5/20 (25%)
Zscan25XP_038945553.1 SCAN 38..120 CDD:396558 6/24 (25%)
KRAB_A-box 241..>269 CDD:413388 3/27 (11%)
COG5048 <348..542 CDD:227381 81/196 (41%)
C2H2 Zn finger 359..379 CDD:275368 8/19 (42%)
C2H2 Zn finger 387..407 CDD:275368 8/19 (42%)
C2H2 Zn finger 415..435 CDD:275368 6/19 (32%)
C2H2 Zn finger 443..463 CDD:275368 7/19 (37%)
C2H2 Zn finger 471..490 CDD:275368 9/21 (43%)
C2H2 Zn finger 498..518 CDD:275368 5/19 (26%)
C2H2 Zn finger 526..545 CDD:275368 4/18 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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