DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kr-h1 and Zfp672

DIOPT Version :9

Sequence 1:	NP_477466.1	Gene:	Kr-h1 / 33861	FlyBaseID:	FBgn0266450	Length:	845	Species:	Drosophila melanogaster
Sequence 2:	NP_001243445.1	Gene:	Zfp672 / 319475	MGIID:	2442105	Length:	468	Species:	Mus musculus

Alignment Length:	412	Identity:	123/412 - (29%)
Similarity:	176/412 - (42%)	Gaps:	82/412 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 AIQQHQKQQQQQQHESITNAAPTAAPSAQRIKTEPVGGFPASAAVVSQVRKPSASKPQ--FKCDQ 198
            |:..|:.:|...:       .|...|...|...:....|..:.|...::...:|..|.  :.|.|
Mouse   114 ALLLHRARQHPPE-------KPHRCPLCARSFRQSALPFHLARAHPPEIITVTAPSPSTLYHCTQ 171

  Fly   199 CGMTFGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTIKPLAN 263
            |...|.|.:...:|::.|                ..|      .|:|
Mouse   172 CPRAFHSSAGLRNHSRIH----------------VVP------SLSD------------------ 196

  Fly   264 VAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYK 328
              .|.:.:.|.:|.|:|:..:.|.||.:.|:||:||:|..|.|.|.....|..|:|.||.|:||.
Mouse   197 --PGTEAHLCGICGKSFSKSSTLTRHLQRHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYA 259

  Fly   329 CDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKG 393
            |..|||.|..|..|.||.|.|.|||||.|:.|.|.|.|...||:|.|:||||:|:.||:  ||:|
Mouse   260 CSDCGRCFSESSTLLRHQRSHQGERPHVCATCGKGFGQRYDLVVHQRSHTGERPFPCPQ--CGRG 322

  Fly   394 FTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEA 458
            ||....|..|.|||||||||||::|.:.|.....|.:|...|.|.|.:||..|.::|....::..
Mouse   323 FTDRSDLTKHLRTHTGEKPYHCELCGKRFTCISNLNVHLRNHAGHKPHKCPECGKSFSVASKLAL 387

  Fly   459 HIKGHANEVPDDEAEAAAASAAASTSAGSSAGSPSLQGVSSNSESSNHSPPSSPPATKKPRQARQ 523
            |.|.|..|               .|:..:..|.....|.|.:....:|            |:||.
Mouse   388 HRKTHLGE---------------RTAECTECGKFFSHGRSLSQHQRSH------------RRARA 425

  Fly   524 PRVSKTVAATLSIPTSSPLSPS 545
            ..::.|  .|.::.|...:.||
Mouse   426 AAMAAT--TTTTVVTEVTIGPS 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h1	NP_477466.1	C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		COG5048	<270..420	CDD:227381	75/149 (50%)
		zf-C2H2	271..293	CDD:278523	7/21 (33%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..309	CDD:290200	11/22 (50%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		zf-H2C2_2	313..338	CDD:290200	13/24 (54%)
		C2H2 Zn finger	329..349	CDD:275368	10/19 (53%)
		zf-H2C2_2	344..366	CDD:290200	13/21 (62%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		zf-H2C2_2	370..396	CDD:290200	15/25 (60%)
		C2H2 Zn finger	385..407	CDD:275368	10/21 (48%)
		zf-H2C2_2	400..424	CDD:290200	15/23 (65%)
		C2H2 Zn finger	415..435	CDD:275368	5/19 (26%)
		zf-C2H2	441..463	CDD:278523	6/21 (29%)
		C2H2 Zn finger	443..463	CDD:275368	5/19 (26%)
Zfp672	NP_001243445.1	C2H2 Zn finger	17..37	CDD:275368
		C2H2 Zn finger	45..65	CDD:275368
		C2H2 Zn finger	73..93	CDD:275368
		C2H2 Zn finger	105..123	CDD:275370	2/8 (25%)
		COG5048	<121..349	CDD:227381	94/278 (34%)
		C2H2 Zn finger	169..189	CDD:275368	6/19 (32%)
		C2H2 Zn finger	204..224	CDD:275368	7/19 (37%)
		C2H2 Zn finger	232..252	CDD:275368	7/19 (37%)
		C2H2 Zn finger	260..280	CDD:275368	10/19 (53%)
		C2H2 Zn finger	288..308	CDD:275368	9/19 (47%)
		C2H2 Zn finger	316..336	CDD:275368	10/21 (48%)
		C2H2 Zn finger	344..364	CDD:275368	5/19 (26%)
		zf-H2C2_2	356..380	CDD:404364	8/23 (35%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		C2H2 Zn finger	400..420	CDD:275368	3/19 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910