DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kr-h1 and GLI4

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_612474.1 Gene:GLI4 / 2738 HGNCID:4320 Length:376 Species:Homo sapiens


Alignment Length:401 Identity:133/401 - (33%)
Similarity:176/401 - (43%) Gaps:50/401 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    79 VPPPLTATTTSVGLGVPPSGGQQEHFELLQTPQQRQMQLQLQ-DQHQQEQQQFVSYQLAIQQHQK 142
            ||.|       |.|..|.:.|.|.|          :.||.|. .||.....   |.::..|....
Human    13 VPSP-------VSLSSPGTPGTQHH----------EPQLHLHGHQHGSPGS---SPKVLSQPSDL 57

  Fly   143 QQQQQQHESITNAA--PTAAPSAQRIKTEPVGGFP---ASAAVVSQVRKPSASKPQFKCDQCGMT 202
            ..|..:...|....  |.:.|..::....|....|   |..|:.|.:|    |.|  :..:|...
Human    58 DLQDVEEVEIGRDTFWPDSEPKPEQAPRSPGSQAPDEGAGGALRSLLR----SLP--RRARCSAG 116

  Fly   203 FGSKSAHTSHTKSHSKNQDLSLNGASGAGVAAPVSTAAIELNDAGLPVGIPKSPTI------KPL 261
            ||.:|  ::...:......:......||.....|..||     || |.|.|:....      :..
Human   117 FGPES--SAERPAGQPPGAVPCAQPRGAWRVTLVQQAA-----AG-PEGAPERAAELGVNFGRSR 173

  Fly   262 ANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERP 326
            ...|.||.|::|..|.|:|...:.|::|.|.||||:|:.|..|.|.|........|.||||.|:|
Human   174 QGSARGAKPHRCEACGKSFKYNSLLLKHQRIHTGEKPYACHECGKRFRGWSGFIQHHRIHTGEKP 238

  Fly   327 YKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCG 391
            |:|..|||||.||....:|:|||.||:|:||..|.:.|.||..||.|.|.|||||||.|.:  ||
Human   239 YECGQCGRAFSHSSHFTQHLRIHNGEKPYKCGECGQAFSQSSNLVRHQRLHTGEKPYACSQ--CG 301

  Fly   392 KGFTCSKQLKVHSRTHTGEKPYHCDICFRDF-GYNHVLKLHRVQHYGSKCYKCTICDETFKNKKE 455
            |.|..|..|..|.|.|||||||.|..|.:.| |.:|..: |...|.|.|.:.|..|.:.|....:
Human   302 KAFIWSSVLIEHQRIHTGEKPYECSDCGKAFRGRSHFFR-HLRTHTGEKPFACGACGKAFGQSSQ 365

  Fly   456 MEAHIKGHANE 466
            :..|.:.|..|
Human   366 LIQHQRVHYRE 376

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 4/19 (21%)
COG5048 <270..420 CDD:227381 75/149 (50%)
zf-C2H2 271..293 CDD:278523 7/21 (33%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
zf-H2C2_2 286..309 CDD:290200 11/22 (50%)
C2H2 Zn finger 301..321 CDD:275368 6/19 (32%)
zf-H2C2_2 313..338 CDD:290200 14/24 (58%)
C2H2 Zn finger 329..349 CDD:275368 10/19 (53%)
zf-H2C2_2 344..366 CDD:290200 11/21 (52%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 370..396 CDD:290200 16/25 (64%)
C2H2 Zn finger 385..407 CDD:275368 9/21 (43%)
zf-H2C2_2 400..424 CDD:290200 13/24 (54%)
C2H2 Zn finger 415..435 CDD:275368 6/20 (30%)
zf-C2H2 441..463 CDD:278523 4/21 (19%)
C2H2 Zn finger 443..463 CDD:275368 4/19 (21%)
GLI4NP_612474.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..97 22/103 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 113..135 4/23 (17%)
COG5048 <181..343 CDD:227381 79/164 (48%)
zf-C2H2 183..205 CDD:278523 7/21 (33%)
C2H2 Zn finger 185..205 CDD:275368 7/19 (37%)
zf-H2C2_2 198..220 CDD:290200 11/21 (52%)
C2H2 Zn finger 213..233 CDD:275368 6/19 (32%)
zf-H2C2_2 228..250 CDD:290200 14/21 (67%)
C2H2 Zn finger 241..261 CDD:275368 10/19 (53%)
zf-H2C2_2 253..278 CDD:290200 11/24 (46%)
C2H2 Zn finger 269..289 CDD:275368 9/19 (47%)
zf-H2C2_2 281..304 CDD:290200 15/24 (63%)
C2H2 Zn finger 297..317 CDD:275368 9/21 (43%)
zf-H2C2_2 310..332 CDD:290200 12/21 (57%)
COG5048 321..>373 CDD:227381 16/52 (31%)
C2H2 Zn finger 325..345 CDD:275368 6/20 (30%)
zf-H2C2_2 337..360 CDD:290200 7/23 (30%)
C2H2 Zn finger 353..373 CDD:275368 4/19 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.