DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr-h1 and PATZ1

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_055138.2 Gene:PATZ1 / 23598 HGNCID:13071 Length:687 Species:Homo sapiens


Alignment Length:461 Identity:115/461 - (24%)
Similarity:172/461 - (37%) Gaps:83/461 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   152 ITNAAPTAAPSAQRIKTEPVGGFPASAAVV-SQVRKPSASKPQ--FKCDQCGMTFGSKSAHTSHT 213
            :|:..|:.|.||..:..:...|.|..|.:: |....|...:..  ..|..||..|...:....|.
Human   247 LTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFGSPGGLREAGILPCGLCGKVFTDANRLRQHE 311

  Fly   214 KSHSKNQDLSLNGASGAGVAA----PVSTAAIELNDAGLPVG-IPKSP-----TIKPLANVAAGA 268
            ..|              ||.:    .:......|.:.|||:. .|..|     |.|.:|      
Human   312 AQH--------------GVTSLQLGYIDLPPPRLGENGLPISEDPDGPRKRSRTRKQVA------ 356

  Fly   269 DPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIH--TKERPYKCDV 331
                |.:|.|.|.....|.||..:|:||:|:.|..|...|..|:.:..|.|.|  :..:||.|..
Human   357 ----CEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQS 417

  Fly   332 CGRAFEHSGKLHRHMR-IHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFT 395
            ||:.|.....|:.|:: :||.||||||..|..:|....:|..|:..|..:.|.:.    ||| :.
Human   418 CGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQV----CGK-YL 477

  Fly   396 CSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQHYG------SKCYKCTI-------CD 447
            .:..:..|.:.|:......|.||.|.|.....||:|...|:|      |:..:..:       |.
Human   478 RAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHGVPLPQVSRHQEPILNGGAAFHCA 542

  Fly   448 ETFKNKKEMEAHIKGHAN--EVPDDEAEAAAASAAASTSAGSSAGSPSL-QGVSSNS-ESSNHSP 508
            .|:.||:..:.   .|.:  |..|...:.:.||...:....|:.||.|. ..|..|. ||.....
Human   543 RTYGNKEGQKC---SHQDPIESSDSYGDLSDASDLKTPEKQSANGSFSCDMAVPKNKMESDGEKK 604

  Fly   509 PSSPPATK--KPRQARQPRVSKTVAATLSIP-------TSSPLSPS---SLSSTY------SPSA 555
            ...|....  :.:......:.|.....|..|       ..||.||.   ||..::      |..|
Human   605 YPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFA 669

  Fly   556 SSMASP 561
            ||:..|
Human   670 SSLVDP 675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 5/19 (26%)
COG5048 <270..420 CDD:227381 48/152 (32%)
zf-C2H2 271..293 CDD:278523 7/21 (33%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
zf-H2C2_2 286..309 CDD:290200 9/22 (41%)
C2H2 Zn finger 301..321 CDD:275368 6/19 (32%)
zf-H2C2_2 313..338 CDD:290200 9/26 (35%)
C2H2 Zn finger 329..349 CDD:275368 6/20 (30%)
zf-H2C2_2 344..366 CDD:290200 11/22 (50%)
C2H2 Zn finger 357..377 CDD:275368 5/19 (26%)
zf-H2C2_2 370..396 CDD:290200 7/25 (28%)
C2H2 Zn finger 385..407 CDD:275368 4/21 (19%)
zf-H2C2_2 400..424 CDD:290200 7/23 (30%)
C2H2 Zn finger 415..435 CDD:275368 8/19 (42%)
zf-C2H2 441..463 CDD:278523 4/28 (14%)
C2H2 Zn finger 443..463 CDD:275368 4/26 (15%)
PATZ1NP_055138.2 BTB_POZ_ZBTB19_PATZ1 14..162 CDD:349516
A-T hook domain 264..272 2/7 (29%)
Zn finger DNA binding domain 294..628 92/365 (25%)
C2H2 Zn finger 294..314 CDD:275368 5/19 (26%)
C2H2 Zn finger 357..377 CDD:275368 7/19 (37%)
zf-C2H2 357..377 CDD:395048 7/19 (37%)
COG5048 <381..518 CDD:227381 43/141 (30%)
C2H2 Zn finger 385..405 CDD:275368 6/19 (32%)
C2H2 Zn finger 415..433 CDD:275368 6/17 (35%)
C2H2 Zn finger 444..464 CDD:275368 5/19 (26%)
C2H2 Zn finger 497..517 CDD:275368 8/19 (42%)
zf-C2H2_assoc3 536..604 CDD:406930 17/70 (24%)
C2H2 Zn finger 607..628 CDD:275370 2/20 (10%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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