DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr-h1 and Zfp940

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_776099.1 Gene:Zfp940 / 233057 MGIID:2446235 Length:566 Species:Mus musculus


Alignment Length:461 Identity:124/461 - (26%)
Similarity:190/461 - (41%) Gaps:81/461 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 LGVPPSGGQQEHFELLQTPQQRQMQ-----------LQLQDQHQQE--QQQFVSYQ--LAIQQ-- 139
            ||.|.:..:....|:.:..::|.::           .|.|....||  :|..|:|:  |.:.|  
Mouse    89 LGKPSTYEELSQREMKEYFRKRSLEDFCFGDGWDGKNQFQTHQNQEYFKQLAVAYEKVLTVNQGI 153

  Fly   140 ----HQ------KQQQQQQHESIT---------------------NAAPTAAPSAQRIK------ 167
                ||      |..:.|..:::|                     ....|:||.::|..      
Mouse   154 VFNNHQRLNAGEKATEIQCEKALTVESDRILPQLTPPGNKVHKDKECGDTSAPESERTHCQRAHC 218

  Fly   168 -------TEPVGGFPASAAVVSQVRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLN 225
                   .|..|.|...:.::...:..:..| .:.|.:||.:|..||..|.|.:.|:..:..:.:
Mouse   219 PQTPQQGKESGGPFGLPSGILGLPQGHTGEK-SYDCKECGKSFTLKSNLTRHRRIHTGERPYTCH 282

  Fly   226 GASGAGVAAP--VSTAAIELNDAGLPVGI-----PKSPTIKPLANV-----AAGADPYQCNVCQK 278
            |...|.....  :|...|.........|:     ....::....|:     .||...|:|..|.|
Mouse   283 GCGKAFTQKSHLMSHQKIHTGKKAYVCGVCGKAFHCDSSLTSHQNIHYHAADAGKKAYECKKCGK 347

  Fly   279 TFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLH 343
            .|...:.||.|.:.||||:||:|:.|.:||....:|:.|.|||:..:.|.|..||::|.....|.
Mouse   348 DFDCHSGLIDHQKVHTGEKPFKCKHCGRLFRFHSHLRAHTRIHSGVKSYDCKECGKSFNLRSNLM 412

  Fly   344 RHMRIHTGERPHKCSVCEKTFIQSGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTH- 407
            ||.|:||||||:.|..|.|.|.|...|..|.:.|||||.|.|..  |||.|:....|..|...| 
Mouse   413 RHHRVHTGERPYTCHGCGKAFSQKSHLTSHQKIHTGEKAYVCGV--CGKAFSRGSSLTSHQNIHY 475

  Fly   408 ----TGEKPYHCDICFRDFGYNHVLKLHRVQHYGSKCYKCTICDETFKNKKEMEAHIKGHANEVP 468
                .|:|.|.|..|.:.||.:..|..|:..|.|.|.:||..|::.|..:..:..|.:.|..|..
Mouse   476 YVVNAGKKVYECKECGKAFGCHSNLSRHQKIHAGEKPFKCRDCEKAFGQRAHLTKHQRIHTGEEG 540

  Fly   469 DDEAEA 474
            .||.::
Mouse   541 PDECQS 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 8/19 (42%)
COG5048 <270..420 CDD:227381 64/154 (42%)
zf-C2H2 271..293 CDD:278523 8/21 (38%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
zf-H2C2_2 286..309 CDD:290200 12/22 (55%)
C2H2 Zn finger 301..321 CDD:275368 7/19 (37%)
zf-H2C2_2 313..338 CDD:290200 10/24 (42%)
C2H2 Zn finger 329..349 CDD:275368 8/19 (42%)
zf-H2C2_2 344..366 CDD:290200 13/21 (62%)
C2H2 Zn finger 357..377 CDD:275368 7/19 (37%)
zf-H2C2_2 370..396 CDD:290200 13/25 (52%)
C2H2 Zn finger 385..407 CDD:275368 7/21 (33%)
zf-H2C2_2 400..424 CDD:290200 9/28 (32%)
C2H2 Zn finger 415..435 CDD:275368 6/19 (32%)
zf-C2H2 441..463 CDD:278523 5/21 (24%)
C2H2 Zn finger 443..463 CDD:275368 4/19 (21%)
Zfp940NP_776099.1 KRAB 6..66 CDD:214630
COG5048 <249..437 CDD:227381 61/188 (32%)
C2H2 Zn finger 253..273 CDD:275368 8/19 (42%)
C2H2 Zn finger 281..301 CDD:275368 3/19 (16%)
C2H2 Zn finger 309..329 CDD:275368 2/19 (11%)
C2H2 Zn finger 342..357 CDD:275370 5/14 (36%)
COG5048 <366..524 CDD:227381 63/159 (40%)
C2H2 Zn finger 370..390 CDD:275368 7/19 (37%)
C2H2 Zn finger 398..418 CDD:275368 8/19 (42%)
C2H2 Zn finger 426..446 CDD:275368 7/19 (37%)
C2H2 Zn finger 454..474 CDD:275368 7/21 (33%)
C2H2 Zn finger 487..507 CDD:275368 6/19 (32%)
C2H2 Zn finger 515..535 CDD:275368 4/19 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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