DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kr-h1 and ZBTB7C

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:XP_016881094.1 Gene:ZBTB7C / 201501 HGNCID:31700 Length:668 Species:Homo sapiens


Alignment Length:277 Identity:80/277 - (28%)
Similarity:113/277 - (40%) Gaps:44/277 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   258 IKPLANVAAGADPYQCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLFSVKENLQVHRRIHT 322
            :||.|:       .||.:|.|......:|.||.||||||:|:.|..|...|:.::.|::|.|.||
Human   407 LKPKAS-------QQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHT 464

  Fly   323 KERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQSGQLVIHM--------RTHTG 379
            .||||.|..|...|.|:..|..|||||||.||::|..|.|:|.:|..|..|:        |...|
Human   465 GERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRG 529

  Fly   380 EKP--YKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYH---CDICFRDFGYNHVLKLHRVQHYGSK 439
            .||  ::......|.|.....:.........||...|   ..:|...        ....:|:.:.
Human   530 RKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPG--------PSPAKHFLAA 586

  Fly   440 CYKCTICDETFKNKKEMEAHIKGHANEVPDDEAEAAAASAAASTSAGSS-------------AGS 491
            ........|..:..:|.:..:.|.|....:..|....|.|.|...|.:.             ||.
Human   587 PKGALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLAGL 651

  Fly   492 PSLQG---VSSNSESSN 505
            |.|.|   |:|.||::|
Human   652 PGLAGLNHVASMSEANN 668

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368
COG5048 <270..420 CDD:227381 57/162 (35%)
zf-C2H2 271..293 CDD:278523 8/21 (38%)
C2H2 Zn finger 273..293 CDD:275368 7/19 (37%)
zf-H2C2_2 286..309 CDD:290200 12/22 (55%)
C2H2 Zn finger 301..321 CDD:275368 6/19 (32%)
zf-H2C2_2 313..338 CDD:290200 12/24 (50%)
C2H2 Zn finger 329..349 CDD:275368 8/19 (42%)
zf-H2C2_2 344..366 CDD:290200 13/21 (62%)
C2H2 Zn finger 357..377 CDD:275368 8/27 (30%)
zf-H2C2_2 370..396 CDD:290200 8/35 (23%)
C2H2 Zn finger 385..407 CDD:275368 2/21 (10%)
zf-H2C2_2 400..424 CDD:290200 4/26 (15%)
C2H2 Zn finger 415..435 CDD:275368 1/19 (5%)
zf-C2H2 441..463 CDD:278523 2/21 (10%)
C2H2 Zn finger 443..463 CDD:275368 2/19 (11%)
ZBTB7CXP_016881094.1 BTB 73..176 CDD:279045
BTB 84..177 CDD:197585
C2H2 Zn finger 415..435 CDD:275368 7/19 (37%)
zf-H2C2_2 430..452 CDD:290200 12/21 (57%)
C2H2 Zn finger 443..463 CDD:275368 6/19 (32%)
zf-H2C2_2 456..480 CDD:290200 12/23 (52%)
C2H2 Zn finger 471..491 CDD:275368 8/19 (42%)
zf-H2C2_2 483..508 CDD:290200 14/24 (58%)
C2H2 Zn finger 499..517 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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