DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr-h1 and lin-29

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_496545.1 Gene:lin-29 / 174830 WormBaseID:WBGene00003015 Length:459 Species:Caenorhabditis elegans


Alignment Length:440 Identity:121/440 - (27%)
Similarity:183/440 - (41%) Gaps:98/440 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   200 GMTFGSKSAHTSH----------TKSHSKNQD--LSLNGA-----SGAGVAAPVSTAAIELNDAG 247
            |.|.||.|  |:|          .:|.|::.|  .|.:||     :|:..:.|...:...||.|.
 Worm    20 GTTTGSGS--TTHFGVGTNFKVSVRSSSRSTDGTDSTDGANSDNVTGSTGSTPAHHSITNLNMAL 82

  Fly   248 LPVGIPKSPTIKPLANVAAGADPY----QCNVCQKTFAVPARLIRHYRTHTGERPFECEFCHKLF 308
            ....|..       |..|:..:|:    |.::.  .|...:.|..|..:..|..|        .|
 Worm    83 SQHSIDS-------ATAASSTNPFPHFNQADLL--NFHQNSLLPHHMFSQFGRYP--------QF 130

  Fly   309 SVKENLQV-HRRIHTKE-RPYKCDVCGRAFEHSGKLHRHMRIHTGERPH-KCSVCEKTFIQSGQL 370
            ..|.::.| .:::..:| :||||..|.:||.:|..|.:|||||.|.:|. .|:.|.|.|.|...|
 Worm   131 EQKPDVGVLQQQMQMREAKPYKCTQCVKAFANSSYLSQHMRIHLGIKPFGPCNYCGKKFTQLSHL 195

  Fly   371 VIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLHRVQH 435
            ..|:|||||||||||...||.|.|:....|:.|||.|..:||:.|:.|::.|.....|..|..:|
 Worm   196 QQHIRTHTGEKPYKCKFTGCDKAFSQLSNLQSHSRCHQTDKPFKCNSCYKCFTDEQSLLDHIPKH 260

  Fly   436 YGSKCYK---CTICDETFKNKKEMEAHIKGHANE----------VPDDEAEAAAASAAASTSAGS 487
            ..||..|   |..|.:::..:..::.|:..||:.          ||.|..:.:..|.......|.
 Worm   261 KESKHLKIHICPFCGKSYTQQTYLQKHMTKHADRSKASNFGNDVVPADPFDPSLLSWNPMQGMGD 325

  Fly   488 SAGSPSLQGVSS-----------NSESSNHSP-------------------PSSPPATKKPRQA- 521
            :|...|...:||           .|:|:|::|                   ...|.:||...:| 
 Worm   326 NAHDSSSFNISSLTDQFAANTMIGSQSTNYNPAFQNSAFSQLFNIRNNRYLSEYPTSTKNGERAP 390

  Fly   522 -----------RQPRVSKTVAATLSIPTSSPLSPSSLSSTYSPSASSMAS 560
                       ::...|.:.|..:...|.|.:..|:.|||.|.||.|.:|
 Worm   391 GFNMITPLENIQRYNGSSSSATAVVTATGSAVVSSTPSSTSSSSAGSSSS 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 7/25 (28%)
COG5048 <270..420 CDD:227381 58/156 (37%)
zf-C2H2 271..293 CDD:278523 4/25 (16%)
C2H2 Zn finger 273..293 CDD:275368 3/19 (16%)
zf-H2C2_2 286..309 CDD:290200 4/22 (18%)
C2H2 Zn finger 301..321 CDD:275368 3/20 (15%)
zf-H2C2_2 313..338 CDD:290200 9/26 (35%)
C2H2 Zn finger 329..349 CDD:275368 9/19 (47%)
zf-H2C2_2 344..366 CDD:290200 11/22 (50%)
C2H2 Zn finger 357..377 CDD:275368 8/19 (42%)
zf-H2C2_2 370..396 CDD:290200 17/25 (68%)
C2H2 Zn finger 385..407 CDD:275368 9/21 (43%)
zf-H2C2_2 400..424 CDD:290200 10/23 (43%)
C2H2 Zn finger 415..435 CDD:275368 5/19 (26%)
zf-C2H2 441..463 CDD:278523 4/24 (17%)
C2H2 Zn finger 443..463 CDD:275368 3/19 (16%)
lin-29NP_496545.1 zf-C2H2 151..173 CDD:278523 11/21 (52%)
C2H2 Zn finger 153..173 CDD:275368 9/19 (47%)
zf-H2C2_2 165..191 CDD:290200 12/25 (48%)
zf-C2H2_8 181..265 CDD:292531 36/83 (43%)
C2H2 Zn finger 182..202 CDD:275368 8/19 (42%)
zf-C2H2 182..202 CDD:278523 8/19 (42%)
zf-H2C2_2 194..221 CDD:290200 17/26 (65%)
C2H2 Zn finger 210..232 CDD:275368 9/21 (43%)
zf-H2C2_2 224..248 CDD:290200 9/23 (39%)
C2H2 Zn finger 240..269 CDD:275368 9/28 (32%)
zf-C2H2 269..291 CDD:278523 3/21 (14%)
C2H2 Zn finger 271..291 CDD:275368 3/19 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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