DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr-h1 and Gfi1

DIOPT Version :9

Sequence 1:NP_477466.1 Gene:Kr-h1 / 33861 FlyBaseID:FBgn0266450 Length:845 Species:Drosophila melanogaster
Sequence 2:NP_001254550.1 Gene:Gfi1 / 14581 MGIID:103170 Length:489 Species:Mus musculus


Alignment Length:463 Identity:124/463 - (26%)
Similarity:191/463 - (41%) Gaps:77/463 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 PKQIWIKDVLKKSGTELLDISKSPAKAVAVKKSPAKDSATTKMVYYSANQLLIKTEQSSQAQFCL 77
            |:...:|.  ||:.:.....|..|..::.::..||...|....|....:::..:...|..:|. .
Mouse    68 PRSFLVKS--KKAHSYHQPRSPGPDYSLRLETVPAPGRAEGGAVSAGESKMEPRERLSPDSQL-T 129

  Fly    78 QVPPPLTATTTSVGLGV------------PPSGGQQEHFELLQTPQQRQMQLQLQDQHQQEQQQF 130
            :.|...:|:..|....|            |||..        .:|...:...:..|:.|.....|
Mouse   130 EAPDRASASPNSCEGSVCDPCSEFEDFWRPPSPS--------VSPASEKSLCRSLDEAQPYTLPF 186

  Fly   131 VSYQLA----------IQQHQKQQQQQQHESIT----NAAPTAAPSAQRIKTEPVGGFPASAAVV 181
            ..|..:          :|.:::....::...::    ..:....|:|:....:..||        
Mouse   187 KPYAWSGLAGSDLRHLVQSYRQCSALERSAGLSLFCERGSEPGRPAARYGPEQAAGG-------- 243

  Fly   182 SQVRKPSASKPQFKCDQCGMTFGSKSAHTSHTKSHSKNQDLSLNG---ASGAGVAAPVSTAAIEL 243
                 ..|.:|    ..||:..|:.||           ..|.|.|   .:.||:....||||..|
Mouse   244 -----AGAGQP----GSCGVAGGATSA-----------AGLGLYGDFAPAAAGLYERPSTAAGRL 288

  Fly   244 -NDAGLPVGIPKSPTIKP-----LANVAAGADPYQCNVCQKTFAVPARLIRHY-RTHTGERPFEC 301
             .|.|..:...||..:|.     ...:..|...|:|..|.|.|:.|..|..|. |:|:|.|||.|
Mouse   289 YQDHGHELHADKSVGVKVESELLCTRLLLGGGSYKCIKCSKVFSTPHGLEVHVRRSHSGTRPFAC 353

  Fly   302 EFCHKLFSVKENLQVHRRIHTKERPYKCDVCGRAFEHSGKLHRHMRIHTGERPHKCSVCEKTFIQ 366
            |.|.|.|....:|:.|:.:|::||.:.|.:||::|:.|..|..|:.||:..||:.|..|.|.|.|
Mouse   354 EMCGKTFGHAVSLEQHKAVHSQERSFDCKICGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQ 418

  Fly   367 SGQLVIHMRTHTGEKPYKCPEPGCGKGFTCSKQLKVHSRTHTGEKPYHCDICFRDFGYNHVLKLH 431
            ...:..|...||||||:||..  |||.|:.|..|..|||.|||.||:.||:|.:.|.....|:.|
Mouse   419 KSDMKKHTFIHTGEKPHKCQV--CGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRH 481

  Fly   432 RVQHYGSK 439
            |...:|.|
Mouse   482 RETQHGLK 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Kr-h1NP_477466.1 C2H2 Zn finger 196..216 CDD:275368 5/19 (26%)
COG5048 <270..420 CDD:227381 66/150 (44%)
zf-C2H2 271..293 CDD:278523 9/22 (41%)
C2H2 Zn finger 273..293 CDD:275368 8/20 (40%)
zf-H2C2_2 286..309 CDD:290200 12/23 (52%)
C2H2 Zn finger 301..321 CDD:275368 7/19 (37%)
zf-H2C2_2 313..338 CDD:290200 9/24 (38%)
C2H2 Zn finger 329..349 CDD:275368 7/19 (37%)
zf-H2C2_2 344..366 CDD:290200 9/21 (43%)
C2H2 Zn finger 357..377 CDD:275368 6/19 (32%)
zf-H2C2_2 370..396 CDD:290200 13/25 (52%)
C2H2 Zn finger 385..407 CDD:275368 10/21 (48%)
zf-H2C2_2 400..424 CDD:290200 13/23 (57%)
C2H2 Zn finger 415..435 CDD:275368 7/19 (37%)
zf-C2H2 441..463 CDD:278523
C2H2 Zn finger 443..463 CDD:275368
Gfi1NP_001254550.1 COG5048 <321..483 CDD:227381 69/163 (42%)
C2H2 Zn finger 324..345 CDD:275368 8/20 (40%)
C2H2 Zn finger 353..373 CDD:275368 7/19 (37%)
zf-H2C2_2 365..390 CDD:290200 9/24 (38%)
C2H2 Zn finger 381..401 CDD:275368 7/19 (37%)
zf-H2C2_2 394..418 CDD:290200 10/23 (43%)
C2H2 Zn finger 409..429 CDD:275368 6/19 (32%)
zf-H2C2_2 421..446 CDD:290200 13/26 (50%)
C2H2 Zn finger 437..457 CDD:275368 10/21 (48%)
C2H2 Zn finger 465..484 CDD:275368 7/18 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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