DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kr-h2 and tmem33

DIOPT Version :9

Sequence 1:	NP_001162894.1	Gene:	Kr-h2 / 33859	FlyBaseID:	FBgn0266449	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_001016411.1	Gene:	tmem33 / 549165	XenbaseID:	XB-GENE-983353	Length:	247	Species:	Xenopus tropicalis

Alignment Length:	234	Identity:	102/234 - (43%)
Similarity:	141/234 - (60%)	Gaps:	8/234 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 LQHFQTNRIDSALWALRLLVIFFTVSYVLPIFTSQQSA--FSKVMLANAAISALRLHQRLPAFAF 104
            :|....|::|:|:|..|...::.:..::|||....::|  :.:.:||||..||||||||||.|..
Frog    15 VQFLMANKLDTAMWLSRWFTVYCSALFILPILGLHEAASFYQRALLANALTSALRLHQRLPHFQL 79

  Fly   105 SREFLARLFAEDSCHYMMYSLIFFNIRPSLLVLIPVLLYSVLHASSYSLKLLDLIGQNSWWGARF 169
            ||.|||:...||||||::|||||.|..|..:.:.||||:|:||||:|:.|:||..|.||....|.
Frog    80 SRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHASTYTKKVLDAKGPNSVPFLRS 144

  Fly   170 IISIVEFQAANILKATAFCEIFIMPYAIVLAFMNHAGLMTPVIYYHYLVMRYSSRRNPYPRNAFA 234
            .:..:.....||||..|..|||:||..:.:.......|:.|.|||.:|.:|||||||||.|..|:
Frog   145 FLEKLNANQQNILKFVACNEIFLMPATVFMLLSGQGSLLQPFIYYRFLTLRYSSRRNPYCRTLFS 209

  Fly   235 ELRITFEALAARSPPAFAKIIR----GGIGFVNRLAPQL 269
            ||||..|.|..:  ||....:|    ..|.|::||||.:
Frog   210 ELRIILEHLVMK--PACPDFVRRLCLSSIAFISRLAPTM 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr-h2	NP_001162894.1	UPF0121	39..268	CDD:281636	101/231 (44%)
tmem33	NP_001016411.1	UPF0121	6..245	CDD:281636	101/231 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	191	1.000	Domainoid score	I3187
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10018
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3750
OMA	1	1.010	-	-		QHG56186
OrthoDB	1	1.010	-	-		D1360050at2759
OrthoFinder	1	1.000	-	-		FOG0004962
OrthoInspector	1	1.000	-	-		oto102777
Panther	1	1.100	-	-	LDO	PTHR12703
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2850
SonicParanoid	1	1.000	-	-		X5298
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110