DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9150 and Dhrs11

DIOPT Version :9

Sequence 1:	NP_608991.2	Gene:	CG9150 / 33856	FlyBaseID:	FBgn0031775	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_038942294.1	Gene:	Dhrs11 / 360583	RGDID:	1307935	Length:	299	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	101/251 - (40%)
Similarity:	143/251 - (56%)	Gaps:	37/251 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MERWQNKLAVVTGASGGIGAACARAMIGAGLRVVGLARREAKLKEL-RESLPRELQANFIPRRCD 64
            ||||:::||:|||||||||||.|||::..||:|||.||....::|| .|..........||.|||
  Rat    76 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD 140

  Fly    65 VSKEDQVQSSFDWIERELEGADVLLNNAGITRETELVTPSNTQKLKEVIDTNVMGVIWCTREAFN 129
            :|.|:.:.|.|..:..:..|.|:.:||||:.|...|::.| |...|::.:.||:.:..|||||:.
  Rat   141 LSNEEDILSMFSAVRSQHSGVDICINNAGMARPDSLLSGS-TSGWKDMFNVNVLALSICTREAYQ 204

  Fly   130 NMKRRG-GEGHVLIINSIAGHQVLNFIDVLPS---FNIYPATKFAITAITETYRQEFQLHSNKIR 190
            :||.|. .:||::.|||:.||:|       |.   .:.|.|||:|:||:||..|||.......||
  Rat   205 SMKERNVDDGHIININSMCGHRV-------PPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIR 262

  Fly   191 VTGICPGAVNTNIFPEEIHFYVKDMARLEPANIADAVMYALRTPPHVQVHEITIKP 246
            .|  |                      |.|.::|:||:|.|.|||||||.:|.::|
  Rat   263 AT--C----------------------LRPEDVAEAVIYVLSTPPHVQVGDIQMRP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9150	NP_608991.2	YdfG	1..251	CDD:226674	101/251 (40%)
CG9150	NP_608991.2	NADB_Rossmann	1..247	CDD:304358	101/251 (40%)
Dhrs11	XP_038942294.1	Mgc4172-like_SDR_c	76..295	CDD:187601	101/251 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337097
Domainoid	1	1.000	151	1.000	Domainoid score	I4244
eggNOG	1	0.900	-	-		E2759_KOG1205
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	188	1.000	Inparanoid score	I3811
OMA	1	1.010	-	-		QHG45743
OrthoDB	1	1.010	-	-		D1190834at2759
OrthoFinder	1	1.000	-	-		FOG0000588
OrthoInspector	1	1.000	-	-		otm44892
orthoMCL	1	0.900	-	-		OOG6_100320
Panther	1	1.100	-	-	O	PTHR43115
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X367
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770