Protein Alignment CG9150 and HSD17B1

DIOPT Version :10

• Sequence 1: NP_608991.2
• Gene: CG9150 / 33856
• FlyBaseID: FBgn0031775
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_001317148.1
• Gene: HSD17B1 / 3292
• HGNCID: 5210
• Length: 329
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 75/270 - (27%)
• Similarity: 111/270 - (41%)
• Gaps: 68/270 - (25%)

  Fly     8 LAVVTGASGGIGAACARAM---------IGAGLRVVGLARREAKLKELRESL---PRELQANFIP 60
            :.::||.|.|||...|..:         :.|.||.:   :.:.:|.|...:|   |..|:.
Human     5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDL---KTQGRLWEAARALACPPGSLET---- 62

  Fly    61 RRCDVSKEDQVQSSFDWIERELEG-ADVLLNNAGITRETELVTPSNT---QKLKEVIDTNVMGVI 121
            .:.||.....|.::   .||..|| .|||:.|||:    .|:.|...   ..:..|:|.||:|.:
Human    63 LQLDVRDSKSVAAA---RERVTEGRVDVLVCNAGL----GLLGPLEALGEDAVASVLDVNVVGTV 120

  Fly   122 WCTREAFNNMKRRGGEGHVLIINSIAGHQVLNFIDVLPSFNIYPATKFAITAITETYR---QEFQ 183
            ...:....:|||| |.|.||:..|:.|...|.|.||      |.|:|||:..:.|:..   ..|.
Human   121 RMLQAFLPDMKRR-GSGRVLVTGSVGGLMGLPFNDV------YCASKFALEGLCESLAVLLLPFG 178

  Fly   184 LHSNKIRVTGICPGAVNTNIF------PEEI----------HFY--------VKDMARLEPANIA 224
            :||..:    |..|.|:|...      |||:          .||        |...|...|..:|
Human   179 VHSLSL----IECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVA 239

  Fly   225 DAVMYALRTP 234
            :..:.|||.|
Human   240 EVFLTALRAP 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9150	NP_608991.2	Rossmann-fold NAD(P)(+)-binding proteins	1..247	CDD:473865	75/270 (28%)
HSD17B1	NP_001317148.1	Rossmann-fold NAD(P)(+)-binding proteins	4..262	CDD:473865	75/270 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	292..329