DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-51 and Ndufv1

DIOPT Version :9

Sequence 1:	NP_001285657.1	Gene:	ND-51 / 33852	FlyBaseID:	FBgn0031771	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_001006973.1	Gene:	Ndufv1 / 293655	RGDID:	1359247	Length:	464	Species:	Rattus norvegicus

Alignment Length:	454	Identity:	369/454 - (81%)
Similarity:	405/454 - (89%)	Gaps:	8/454 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TLPASLHVQRFQSTQAPPPGTPPPQTKTKFGPLADEDRIFTNLYGRHDWRLKGALKRGDWYKTKE 82
            ::|..:.|:....|.||        .||.||.|.||||||||||||||||||||.:|||||||||
  Rat    11 SVPVRVSVRLSSGTTAP--------KKTSFGSLKDEDRIFTNLYGRHDWRLKGAQRRGDWYKTKE 67

  Fly    83 IVLKGADWIVNEIKTSGLRGRGGAGFPSGMKWSFMNKPGDGRPKYLVVNADEGEPGTCKDREIMR 147
            |:|||.|||:.|:||||||||||||||:|:||||||||.||||||||||||||||||||||||||
  Rat    68 ILLKGPDWILGEMKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREIMR 132

  Fly   148 HDPHKLVEGCLIAGRAMGAQAAYIYIRGEFYNEASNMQLAIAEAYQAGLIGKNACGTGYDFDVFM 212
            |||||||||||:.||||||:||||||||||||||||:|:||.|||:|||||||||.:.||||||:
  Rat   133 HDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACDSDYDFDVFV 197

  Fly   213 HRGAGAYICGEETALIESLEGKQGKPRLKPPFPADVGVFGCPTTVTNVETVAVAPTICRRGGVWF 277
            .|||||||||||||||||:||||||||||||||||||||||||||.|||||||:||||||||.||
  Rat   198 VRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWF 262

  Fly   278 ASFGRTRNSGTKLFNISGHVNRPCTVEEEMSIPLKELIERHCGGVTGGWDNLLGVIPGGSSTPII 342
            |.|||.|||||||||||||||.|||||||||:|||||||:|.|||.|||||||.|||||||||:|
  Rat   263 AGFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKELIEKHAGGVLGGWDNLLAVIPGGSSTPLI 327

  Fly   343 PKNVCDDVIMDFDGLIAAQTSLGTAAIIVMDKSTDVIKAIARLISFYKHESCGQCTPCREGIGWM 407
            ||:||:.|:||||.|:.|||.|||||:|||:.|||::|||||||.||||||||||||||||:.||
  Rat   328 PKSVCETVLMDFDALVQAQTGLGTAAVIVMNSSTDIVKAIARLIEFYKHESCGQCTPCREGVDWM 392

  Fly   408 NKIMTRFVKGDAQPAEIDMLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPEIEKRMQLHAKR 471
            ||:|.|||||||:|||||.||||||||||||||||||||||||||||||||||:|.|||..|::
  Rat   393 NKVMARFVKGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEDRMQRFAQQ 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-51	NP_001285657.1	PRK13596	50..474	CDD:237441	360/422 (85%)
		Complex1_51K	95..264	CDD:279808	150/168 (89%)
		SLBB	290..342	CDD:287499	45/51 (88%)
		NADH_4Fe-4S	381..462	CDD:287548	73/80 (91%)
Ndufv1	NP_001006973.1	PRK13596	35..453	CDD:237441	359/417 (86%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353748
Domainoid	1	1.000	327	1.000	Domainoid score	I1142
eggNOG	1	0.900	-	-		E1_COG1894
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5151
Inparanoid	1	1.050	789	1.000	Inparanoid score	I490
OMA	1	1.010	-	-		QHG54201
OrthoDB	1	1.010	-	-		D272111at33208
OrthoFinder	1	1.000	-	-		FOG0003103
OrthoInspector	1	1.000	-	-		oto96953
orthoMCL	1	0.900	-	-		OOG6_101044
Panther	1	1.100	-	-	LDO	PTHR11780
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770