DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-51 and SPBC18E5.10

DIOPT Version :9

Sequence 1:	NP_001285657.1	Gene:	ND-51 / 33852	FlyBaseID:	FBgn0031771	Length:	474	Species:	Drosophila melanogaster
Sequence 2:	NP_595857.1	Gene:	SPBC18E5.10 / 2540740	PomBaseID:	SPBC18E5.10	Length:	452	Species:	Schizosaccharomyces pombe

Alignment Length:	419	Identity:	163/419 - (38%)
Similarity:	241/419 - (57%)	Gaps:	6/419 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 RIFTNLYGRHDWRLKGALKRGDWYKTKEIVLKGADWIVNEIKTSGLRGRGGAGFPSGMKWSFMNK 119
            |:|.||..:...|:..||..|::....||:......|:..::.|.|||||..|||:|.|...:.|
pombe    33 RMFPNLIEKRIRRIDDALADGEYENLSEILKYDPLNIIELVQESELRGRGRYGFPTGEKMLSLYK 97

  Fly   120 P-----GDGRPKYLVVNADEGEPGTCKDREIMRHDPHKLVEGCLIAGRAMGAQAAYIYIRGEFYN 179
            .     |......::|||.|.:.|:.|||.::||:|||::||.:||.||:.|.|.|::||.::|.
pombe    98 ATSSERGRKEKPVVIVNAAENDIGSFKDRLLLRHEPHKIIEGAIIAARAVEASACYLFIRKDYYE 162

  Fly   180 EASNMQLAIAEAYQAGLIGKNACGTGYDFDVFMHRGAGAYICGEETALIESLEGKQGKPRLKPPF 244
            |...||..|.:||...|:|||..||....::.:|.|||:||.|||:|||:||:|:...|.:....
pombe   163 ETVMMQKCIIQAYAKKLLGKNLLGTSIGLELLIHPGAGSYITGEESALIQSLQGEFPVPDIPINN 227

  Fly   245 PADVGVFGCPTTVTNVETVAVAPTICRRGGVWFASFGRTRNSGTKLFNISGHVNRPCTVEEEMSI 309
            ....|:||.||.|.|||||:..|.|.::|..:|.|.||..|.|||||:|||.||.|..:|..|||
pombe   228 TITSGLFGLPTLVLNVETVSNLPAIIKKGPKFFISMGRPNNRGTKLFSISGEVNEPNVIEACMSI 292

  Fly   310 PLKELIERHCGGVTGGWDNLLGVIPGGSSTPIIPKNVCDDVIMDFDGLIAAQTSLGTAAIIVMDK 374
            |||:|||.:.|||.|||:.|:|:.|||..:.|:.||.|:.|.||||.|.|..:||||.::||::.
pombe   293 PLKDLIENYAGGVRGGWNKLVGIFPGGPCSGILNKNQCEQVTMDFDSLKALDSSLGTGSVIVLND 357

  Fly   375 STDVIKAIARLISFYKHESCGQCTPCREGIGWMNKIMTRFVKGDAQPAEI-DMLWEISKQIEGHT 438
            ...:.:::.....||...:|..|..||:|:..:.:.:.....|.|..::: ||..:.:.......
pombe   358 HDQIFESLLNFAKFYSTNTCHTCPVCRDGVEDVIETLKGLKDGHAHLSQLKDMFSKFNMPSSSKV 422

  Fly   439 ICALGDGAAWPVQGLIRHFRPEIEKRMQL 467
            .|..||.....:..:.|:|..:|..|.::
pombe   423 FCGFGDSMRHQIHSIQRNFPDQITFRTKV 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-51	NP_001285657.1	PRK13596	50..474	CDD:237441	163/419 (39%)
		Complex1_51K	95..264	CDD:279808	76/173 (44%)
		SLBB	290..342	CDD:287499	29/51 (57%)
		NADH_4Fe-4S	381..462	CDD:287548	16/81 (20%)
SPBC18E5.10	NP_595857.1	NuoF	21..452	CDD:224806	163/419 (39%)
		Complex1_51K	73..250	CDD:279808	77/176 (44%)
		SLBB	273..323	CDD:287499	29/49 (59%)
		NADH_4Fe-4S	365..445	CDD:287548	16/79 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	146	1.000	Domainoid score	I1134
eggNOG	1	0.900	-	-		E1_COG1894
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	303	1.000	Inparanoid score	I595
OMA	1	1.010	-	-		QHG54201
OrthoFinder	1	1.000	-	-		FOG0003103
OrthoInspector	1	1.000	-	-		otm47231
orthoMCL	1	0.900	-	-		OOG6_101044
Panther	1	1.100	-	-	LDO	PTHR11780
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R803
SonicParanoid	1	1.000	-	-		X2074
TreeFam	1	0.960	-	-
	13	12.860