DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and PRAF1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_565144.1	Gene:	PRAF1 / 844030	AraportID:	AT1G76950	Length:	1103	Species:	Arabidopsis thaliana

Alignment Length:	536	Identity:	113/536 - (21%)
Similarity:	187/536 - (34%)	Gaps:	178/536 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PKKKESDYEDEFSDES----DDDGVQQQAAAANQMEVLIPH-----------DDLDPPSKLPEDL 68
            ||..|.:.....|::|    |:..:|.:.:.::...|.:..           ||.|
plant   180 PKSAEPEVPPTDSEKSHVALDNKNMQTKVSGSDGFRVSVSSAQSSSSHGSAADDSD--------- 235

  Fly    69 LATLEKTPGQMLIAGMVTWDLTGKRDRKNVTKVRPNLYSFHRFTEEKYRYVASGPSAAHTILINM 133
                  ..|.:.|.|.|..|        ||.||
plant   236 ------ALGDVYIWGEVICD--------NVVKV-------------------------------- 254

  Fly   134 DRKALGFGRNPSGQLGLSQDIKLAEKPTIIPALEQ---LNIVQAAVGRHHTLFLTDTGTVYACGE 195
                 |..:|.| .|....|: |..||     ||.   |::.|.|.|..|..|:|..|.::..||
plant   255 -----GIDKNAS-YLTTRTDV-LVPKP-----LESNIVLDVHQIACGVRHAAFVTRQGEIFTWGE 307

  Fly   196 NKSGQCGVGNTHANIYSP---------TPINYRGPPIIRIGCGAEFSVILDIKGSLHTF--GLPE 249
            ...|:.|.| ...:::.|         :.:::       :.||...:..:.:.|.|:|:  |...
plant   308 ESGGRLGHG-IGKDVFHPRLVESLTATSSVDF-------VACGEFHTCAVTLAGELYTWGDGTHN 364

  Fly   250 YGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDS 314
            .|.|||.:|..:::            ||::...:|           |:.:...:||..||..|.|
plant   365 VGLLGHGSDISHWI------------PKRIAGSLE-----------GLHVASVSCGPWHTALITS 406

  Fly   315 KKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSLIVNEL---------- 369
            ..|::::|.|.||.|||.:.:....||.::  ...|....:|.||...:..|.|:
plant   407 YGRLFTFGDGTFGVLGHGDKETVQYPREVE--SLSGLRTIAVSCGVWHTAAVVEIIVTQSNSSSV 469

  Fly   370 --GLLFLFGQNKKT----GEANMYPKP--VQDLSGWNITDIGCANT-SIMISADDTLIAWGASPT 425
              |.||.:|...|.    |:.:...||  |..|..:|...|.|.:: ::.::....:...| |..
plant   470 SSGKLFTWGDGDKNRLGHGDKDPRLKPTCVPALIDYNFHKIACGHSLTVGLTTSGQVFTMG-STV 533

  Fly   426 FGELGIGEFQKSSTVPKEV-PKLDNIKIPQVTMGYSHTVLL------------------------ 465
            :|:|  |..|....:|..| .||.:..:.:::.|..|...|
plant   534 YGQL--GNLQTDGKLPCLVEDKLASEFVEEISCGAYHVAALTSRNEVYTWGKGANGRLGHGDLED 596

  Fly   466 --VDTTHEATKQKYEK 479
              |.|..||.|.::.|
plant   597 RKVPTIVEALKDRHVK 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	15/47 (32%)
		RCC1_2	171..200	CDD:290274	9/28 (32%)
		RCC1	188..236	CDD:278826	9/56 (16%)
		RCC1	239..312	CDD:278826	17/74 (23%)
		RCC1	317..366	CDD:278826	14/48 (29%)
		RCC1	414..465	CDD:278826	12/51 (24%)
PRAF1	NP_565144.1	PH_PLC_plant-like	14..124	CDD:270171
		ATS1	238..628	CDD:227511	102/463 (22%)
		FYVE	627..695	CDD:214499
		COG1340	<828..909	CDD:224259
		BRX_N	879..>908	CDD:404581
		BRX	1022..1077	CDD:400608
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820