DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9135 and AT5G12350

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_568268.3	Gene:	AT5G12350 / 831110	AraportID:	AT5G12350	Length:	1075	Species:	Arabidopsis thaliana

Alignment Length:	382	Identity:	99/382 - (25%)
Similarity:	159/382 - (41%)	Gaps:	67/382 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 GFGRNPSG----QLGLSQDIKLAEKPTIIP-ALEQ---LNIVQAAVGRHHTLFLTDTGTVYACGE 195
            |.|....|    ::|.|.|||:   .:::| |||.   |::...|.|..|.:.:|..|..::.||
plant   273 GIGEGVLGGGNRRVGSSFDIKM---DSLLPKALESTIVLDVQNIACGGQHAVLVTKQGESFSWGE 334

  Fly   196 NKSGQCGVGNTHANIYSPTPINYRGPPIIR-IGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDA 259
            ...|:.|.| ..:||..|..|:......|. :.||...|..:.:.|.|:|:|..::|.|||..:.
plant   335 ESEGRLGHG-VDSNIQQPKLIDALNTTNIELVACGEFHSCAVTLSGDLYTWGKGDFGVLGHGNEV 398

  Fly   260 KYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDSKKRVYSWGFG 324
            .::|            ||:|...:|           |:.:...|||..||..:.|..:::::|.|
plant   399 SHWV------------PKRVNFLLE-----------GIHVSSIACGPYHTAVVTSAGQLFTFGDG 440

  Fly   325 GFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSV--FCGSTFSLIVNEL------------GLLFLF 375
            .||.|||.:.|...:||.:...    :|.|:|  .||...:..|.|:            |.||.:
plant   441 TFGVLGHGDKKSVFIPREVDSL----KGLRTVRAACGVWHTAAVVEVMVGSSSSSNCSSGKLFTW 501

  Fly   376 GQNKK--TGEANMYPKPVQD----LSGWNITDIGCANT-SIMISADDTLIAWGASPTFGELGIGE 433
            |...|  .|..|..||.|..    |...|...:.|.:: ::.::....:...| ||.:|:|  |.
plant   502 GDGDKGRLGHGNKEPKLVPTCVAALVEPNFCQVACGHSLTVALTTSGHVYTMG-SPVYGQL--GN 563

  Fly   434 FQKSSTVPKEVP-KLDNIKIPQVTMGYSHTVLLVDTTHEAT--KQKYEKMPEYTIDD 487
            .......|..|. ||....:.::..|..|..:|...|...|  |....::....:||
plant   564 SHADGKTPNRVEGKLHKSFVEEIACGAYHVAVLTSRTEVYTWGKGSNGRLGHGDVDD 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	16/52 (31%)
		RCC1_2	171..200	CDD:290274	7/28 (25%)
		RCC1	188..236	CDD:278826	14/48 (29%)
		RCC1	239..312	CDD:278826	19/72 (26%)
		RCC1	317..366	CDD:278826	15/50 (30%)
		RCC1	414..465	CDD:278826	12/51 (24%)
AT5G12350	NP_568268.3	PH_PLC_plant-like	19..129	CDD:270171
		RCC1_2	310..339	CDD:290274	7/28 (25%)
		RCC1	327..375	CDD:278826	14/48 (29%)
		RCC1	378..428	CDD:278826	19/72 (26%)
		RCC1	432..480	CDD:278826	15/51 (29%)
		RCC1	496..544	CDD:278826	13/47 (28%)
		RCC1	547..596	CDD:278826	12/51 (24%)
		RCC1	601..648	CDD:278826	4/20 (20%)
		FYVE	652..719	CDD:279674
		BRX_N	911..946	CDD:290432
		BRX	1006..1060	CDD:285568
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820