Protein Alignment CG9135 and RCC1L

DIOPT Version :9

• Sequence 1: NP_001285655.1
• Gene: CG9135 / 33850
• FlyBaseID: FBgn0031769
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_110425.2
• Gene: RCC1L / 81554
• HGNCID: 14948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 96/368 - (26%)
• Similarity: 151/368 - (41%)
• Gaps: 103/368 - (27%)

  Fly    97 NVTKV------RPNLYSFHRFTEEK---YRYVASGPS--------------------AAHTILIN 132
            :||||      :.:...|||..::|   |.||.. ||                    .||::::.
Human   127 DVTKVWGMGLNKDSQLGFHRSRKDKTRGYEYVLE-PSPVSLPLDRPQETRVLQVSCGRAHSLVLT 190

  Fly   133 MDRKALGFGRNPSGQLGLSQDIKLAEKPTI-----IPALEQLN--IVQAAVGRHHTLFLTDTGTV 190
            ........|.|..||.|.    |:.|....     :..::..:  :||.|.|:.|:|||||.|.|
Human   191 DREGVFSMGNNSYGQCGR----KVVENEIYSESHRVHRMQDFDGQVVQVACGQDHSLFLTDKGEV 251

  Fly   191 YACGENKSGQCGVGNTHANI-YSPTPI--NYRGPPIIRIGCGAEFSVILDIKGSLHTFGLPEYGQ 252
            |:||....||.|:|  |.|| .|||.:  :..|..:|::....:..:.:...|.|..:|..||.|
Human   252 YSCGWGADGQTGLG--HYNITSSPTKLGGDLAGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQ 314

  Fly   253 LGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGV-QIVDFACGNNHTVAIDSKK 316
            |...||:.. ||..: ..||                      .|| ::...|||......::.:.
Human   315 LASVTDSTQ-VNVPR-CLHF----------------------SGVGKVRQAACGGTGCAVLNGEG 355

  Fly   317 RVYSWGFGGFGR----LGHAEPKDEMVPRL---MKFFDTQGRGGRSVFCG-STFSLIVNELGLLF 373
            .|:.||:|..|:    :..|.|  ||:|..   :..|:.:.:..| :.|| |.|:.:.|: |.||
Human   356 HVFVWGYGILGKGPNLVESAVP--EMIPPTLFGLTEFNPEIQVSR-IRCGLSHFAALTNK-GELF 416

  Fly   374 LFGQNKK----TG--EANMYPKPVQDLSGWNIT------DIGC 404
            ::|:|.:    .|  |...:|        |.:|      |:.|
Human   417 VWGKNIRGCLGIGRLEDQYFP--------WRVTMPGEPVDVAC 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	13/51 (25%)
		RCC1_2	171..200	CDD:290274	15/28 (54%)
		RCC1	188..236	CDD:278826	17/50 (34%)
		RCC1	239..312	CDD:278826	18/73 (25%)
		RCC1	317..366	CDD:278826	16/56 (29%)
		RCC1	414..465	CDD:278826
RCC1L	NP_110425.2	RCC1 1. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	58..124
		RCC1 2. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	128..191		15/63 (24%)
		RCC1	130..189	CDD:278826	13/59 (22%)
		RCC1_2	176..205	CDD:290274	4/28 (14%)
		RCC1 3. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	193..247		15/57 (26%)
		RCC1	195..245	CDD:278826	13/53 (25%)
		RCC1_2	232..261	CDD:290274	15/28 (54%)
		RCC1 4. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	248..300		17/53 (32%)
		RCC1	248..298	CDD:278826	17/51 (33%)
		RCC1	301..351	CDD:278826	18/73 (25%)
		RCC1 5. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	302..353		18/74 (24%)
		RCC1 6. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	354..411		16/59 (27%)
		RCC1_2	396..425	CDD:290274	11/30 (37%)
		RCC1 7. /evidence=ECO:0000255, ECO:0000305|PubMed:28608466	412..461		12/49 (24%)
		RCC1	412..455	CDD:278826	12/49 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820