DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and HECTD3

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_078878.3	Gene:	HECTD3 / 79654	HGNCID:	26117	Length:	861	Species:	Homo sapiens

Alignment Length:	145	Identity:	29/145 - (20%)
Similarity:	51/145 - (35%)	Gaps:	46/145 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 IEKSKEG---------HVTPVDGVQIVDF------ACGNNHTVAIDSKKRVYSWGFGGFGRLGHA 332
            :|:|||.         .|.|...:.::.:      .||:.. |.:|:.:::        .|....
Human   708 LEESKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPE-VTVDALRKL--------TRFEDF 763

  Fly   333 EPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSLIVNELGLLFLFGQNKKTGEANMYPKPVQDLSGW 397
            ||.|..|....:..:......||.|             |.|:.|:::......:||    |..|:
Human   764 EPSDSRVQYFWEALNNFTNEDRSRF-------------LRFVTGRSRLPARIYIYP----DKLGY 811

  Fly   398 NITDI-----GCANT 407
            ..||.     .|::|
Human   812 ETTDALPESSTCSST 826

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826
		RCC1_2	171..200	CDD:290274
		RCC1	188..236	CDD:278826
		RCC1	239..312	CDD:278826	9/43 (21%)
		RCC1	317..366	CDD:278826	8/48 (17%)
		RCC1	414..465	CDD:278826
HECTD3	NP_078878.3	APC10-HECTD3	238..371	CDD:176487
HECTD3	NP_078878.3	HECT	579..845	CDD:366212	29/145 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010