DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and rcbtb2

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_005173422.1	Gene:	rcbtb2 / 794652	ZFINID:	ZDB-GENE-071016-3	Length:	527	Species:	Danio rerio

Alignment Length:	398	Identity:	102/398 - (25%)
Similarity:	157/398 - (39%)	Gaps:	84/398 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 SGPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTIIPALEQLNIV-----QAAVGRHH 180
            :||   |.::...|.:...:|.|...|||..     .....:.|||...|::     :.:.|.||
Zfish    83 TGP---HVVIATADGEVYAWGHNGYSQLGNG-----TTNHGLTPALVSTNLIGKRVTEVSCGSHH 139

  Fly   181 TLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPIN----YRGPPIIRIGCGAEFSVILDIKGS 241
            |:.||..|.|||.|.|.|||.|.|:| ||  .|||..    .:...::.|.||...|:.:...|.
Zfish   140 TIALTTDGEVYAWGYNNSGQVGSGST-AN--QPTPRRVSSCLQNKVVVNIACGQLCSMAVLDNGE 201

  Fly   242 LHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGN 306
            .:.:|....||||...      |.|      :.:|.:            :..:.|:.|:..|||.
Zfish   202 TYGWGYNCNGQLGLGN------NGN------QQTPCR------------IAALQGINIIQVACGY 242

  Fly   307 NHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTF-SLIVNELG 370
            .||:|:..:..|||||...:|:||.....::.||.|:..  .:.|......|.::. |....:.|
Zfish   243 AHTLALTDEGFVYSWGANSYGQLGTGNKSNQAVPTLINM--DKERMVEVAACHTSHTSAAKTQSG 305

  Fly   371 LLFLFGQNKKTGEANMYPKPVQDLSGWNITD--IGCANTS------IMISADDTL-IAWGASPTF 426
            .:.::||.:  |:|..||    .|:.:..||  ..|..|.      :.:..||.| :|......|
Zfish   306 QVLMWGQCR--GQAVAYP----HLTHFTSTDDVFACFATPAVTWHLLSVDGDDYLTVAQSLKREF 364

  Fly   427 GELGIGEFQ-----KSSTVPKEVPKLDNIKIPQVTMGYSHTVLLVDTTHEATKQ-------KYEK 479
            ....|.:.:     |...|.|.:.|:          ...|...|::.|.|.|.:       .|..
Zfish   365 DSPDISDLKFLVDGKCIHVHKALLKI----------RCEHFRALLNETDEETIEIHQFSYLVYRA 419

  Fly   480 MPEYTIDD 487
            ..||...|
Zfish   420 FLEYLYTD 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	13/49 (27%)
		RCC1_2	171..200	CDD:290274	13/33 (39%)
		RCC1	188..236	CDD:278826	21/51 (41%)
		RCC1	239..312	CDD:278826	16/72 (22%)
		RCC1	317..366	CDD:278826	14/49 (29%)
		RCC1	414..465	CDD:278826	11/56 (20%)
rcbtb2	XP_005173422.1	RCC1	40..89	CDD:278826	3/8 (38%)
		RCC1	93..143	CDD:278826	14/54 (26%)
		RCC1	146..196	CDD:278826	21/52 (40%)
		RCC1	199..248	CDD:278826	16/72 (22%)
		RCC1	251..299	CDD:278826	13/49 (27%)
		BTB	364..460	CDD:279045	15/74 (20%)
		BTB	371..463	CDD:197585	13/67 (19%)
		SPOP_C_like	463..521	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910