DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and hectd3

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001072497.1	Gene:	hectd3 / 779952	XenbaseID:	XB-GENE-5937967	Length:	845	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	76/208 - (36%)	Gaps:	52/208 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RRPKKKESDYEDEFSDES-DDDGVQQQAAAANQMEVLIPHDDLDPPSKLP--------------- 65
            |.|.:.|..:|.:|..|. .|.|...:.:.|:..|.|.| ...|.|..||
Frog   503 RWPVRYEQWWECKFIAEGIIDQGGGFRDSLADISEELCP-SSADIPVPLPFFVRTSNQGNGTGEA 566

  Fly    66 EDL---------LATLEKTPGQML-------------IAGMVTWDLTGK-----RDRKNVTKVRP 103
            :|:         ||..|.. ||::             :.|:|...|||:     :|...|..:..
Frog   567 QDMYVPNPSCKDLAKYEWI-GQLMGAALRGKEFLVLALPGLVWKQLTGEEVSWSKDFPAVDSLLV 630

  Fly   104 NLYS-FHRFTEEKYRYVASGPSAAHTILINMDRKALGFGRNPSGQLGLSQD----IKLAEKPTII 163
            .|.. .....||.:.:..||.....|:|  .|:|.:......|....|.:|    |::.:|..:.
Frog   631 KLLEMMELMDEETFEFKFSGELTYTTVL--SDQKMVELVPGGSNISVLYKDRVEFIRMVQKARLE 693

  Fly   164 PALEQLNIVQAAV 176
            .:.||:..:||.:
Frog   694 ESKEQIGALQAGL 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	9/42 (21%)
		RCC1_2	171..200	CDD:290274	2/6 (33%)
		RCC1	188..236	CDD:278826
		RCC1	239..312	CDD:278826
		RCC1	317..366	CDD:278826
		RCC1	414..465	CDD:278826
hectd3	NP_001072497.1	APC10-HECTD3	222..355	CDD:176487
hectd3	NP_001072497.1	HECTc	512..837	CDD:421431	44/199 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010