DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9135 and Als2

DIOPT Version :9

Sequence 1:NP_001285655.1 Gene:CG9135 / 33850 FlyBaseID:FBgn0031769 Length:487 Species:Drosophila melanogaster
Sequence 2:NP_001153420.2 Gene:Als2 / 74018 MGIID:1921268 Length:1651 Species:Mus musculus


Alignment Length:240 Identity:53/240 - (22%)
Similarity:82/240 - (34%) Gaps:79/240 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   127 HTILINMDRKALGFGRNPSGQLGLSQDIKLA-EKPTIIPALEQLNIVQAAVGRHHTLFLTDTGTV 190
            |.:|:..|.:...||..|    ..|:..::. ..|.:..||...:::..|.|..|:..:|::|.|
Mouse    52 HGVLLTEDGEVYSFGTLP----WKSESAEICPSSPLLESALVGHHVITVATGSFHSGAVTESGVV 112

  Fly   191 YACGENKSGQCGVGNTHANIYSPTPINYRGPPIIRIGCGAEFSVILDIKGSLHTFGLPEYGQLGH 255
            |..|||.:|||.|.|..   |.|.|                                        
Mouse   113 YMWGENAAGQCAVANQQ---YVPEP---------------------------------------- 134

  Fly   256 NTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDSKKRVYS 320
                               ||..:       .:...:|...|:|:..|||..||:|:...:.:::
Mouse   135 -------------------SPVSI-------SDSETSPSLAVRILQLACGEEHTLALSLSREIWA 173

  Fly   321 WGFG-GFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSL 364
            ||.| ..|.:....|    |.:..|.....||....|.||:..||
Mouse   174 WGTGCQLGLITTTFP----VTKPQKVEHLAGRVVLQVACGAFHSL 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9135NP_001285655.1 RCC1 139..184 CDD:278826 10/45 (22%)
RCC1_2 171..200 CDD:290274 10/28 (36%)
RCC1 188..236 CDD:278826 14/47 (30%)
RCC1 239..312 CDD:278826 10/72 (14%)
RCC1 317..366 CDD:278826 14/49 (29%)
RCC1 414..465 CDD:278826
Als2NP_001153420.2 RCC1 1. /evidence=ECO:0000305 59..108 11/52 (21%)
RCC1_2 93..122 CDD:290274 10/28 (36%)
RCC1 2. /evidence=ECO:0000305 109..167 25/126 (20%)
RCC1 109..165 CDD:278826 24/124 (19%)
RCC1 3. /evidence=ECO:0000305 169..218 14/50 (28%)
RCC1 170..216 CDD:278826 14/49 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 425..462
RCC1 4. /evidence=ECO:0000305 519..570
RCC1 521..568 CDD:278826
RCC1 5. /evidence=ECO:0000305 572..621
RCC1 573..619 CDD:278826
RhoGEF 689..873 CDD:295373
PH_alsin 899..1004 CDD:241423
PH 920..998 CDD:278594
COG4642 1043..1182 CDD:226989
MORN 1 1043..1065
MORN 1043..1063 CDD:280628
MORN 2 1066..1088
MORN 3 1094..1116
MORN 1094..1114 CDD:280628
MORN 4 1117..1139
MORN 5 1145..1167
COG4642 1166..>1266 CDD:226989
MORN 6 1169..1191
MORN 7 1192..1214
MORN 8 1215..1238
VPS9 1548..1647 CDD:280383
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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