DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and Rcbtb1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001347539.1	Gene:	Rcbtb1 / 71330	MGIID:	1918580	Length:	531	Species:	Mus musculus

Alignment Length:	414	Identity:	99/414 - (23%)
Similarity:	159/414 - (38%)	Gaps:	85/414 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 GPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTIIP-ALEQL---NIVQAAVGR-HHT 181
            |.||...|.:..:.:...||.|.|..||...:     :.|::| .||.|   .|...:.|. .|.
Mouse    28 GTSANEAIYVTDNDEVFVFGLNYSNCLGTGDN-----QSTLVPKKLEALCGKKIKSLSYGSGPHV 87

  Fly   182 LFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPI--NYRGPPIIRIGCGAEFSVILDIKGSLHT 244
            |..|:.|.|||.|.|...|.|.|.|:..| :|..:  |.....:|.:.||:..|:.|...|.|..
Mouse    88 LLTTEDGVVYAWGHNGYSQLGNGTTNQGI-APVQVCTNLLIKQVIEVACGSHHSMALAADGELFA 151

  Fly   245 FGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHT 309
            :|....||:|..:.|.            :.:|:||...:...:           :|:.|||...:
Mouse   152 WGYNNCGQVGSGSTAN------------QPTPRKVTNCLHTKR-----------VVNIACGQTSS 193

  Fly   310 VAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSLIVNELGLLFL 374
            :|:.....||.||:.|.|:||.....:::.|  ::.....|.....:.||...:|.:.:.|||:.
Mouse   194 MAVLDSGEVYGWGYNGNGQLGLGNNGNQLTP--VRVAALHGMCVNQIVCGYAHTLALTDEGLLYA 256

  Fly   375 FGQNK----KTGEANMYPKPVQ---------DLSGWNITDIGCANT--------------SIMI- 411
            :|.|.    .||..|....|.|         :::..:.|....|.|              |:::
Mouse   257 WGANTYGQLGTGSKNNLLSPTQIMVEKERVIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILP 321

  Fly   412 ------SADDTLIAWGASPTFGELGIGEFQKSSTVPKEV------PKLDNIKIPQVTMGYSH--- 461
                  ..||....:|.......|...|.:...||.:.:      |:..::|. ::...|.|
Mouse   322 HLTHFCCTDDVFACFGTPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKF-RIDGKYIHVHK 385

  Fly   462 TVLLVDTTH-EATKQKY--EKMPE 482
            .||.:...| .:..|.|  |.|.|
Mouse   386 AVLKIRCEHFRSMFQSYWNEDMKE 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	15/49 (31%)
		RCC1_2	171..200	CDD:290274	11/29 (38%)
		RCC1	188..236	CDD:278826	17/49 (35%)
		RCC1	239..312	CDD:278826	14/72 (19%)
		RCC1	317..366	CDD:278826	13/48 (27%)
		RCC1	414..465	CDD:278826	12/59 (20%)
Rcbtb1	NP_001347539.1	RCC1 1	40..91		15/55 (27%)
		ATS1	43..>316	CDD:227511	75/303 (25%)
		RCC1 2	93..145		18/52 (35%)
		RCC1 3	147..198		15/73 (21%)
		RCC1 4	199..250		13/52 (25%)
		RCC1 5	252..302		12/49 (24%)
		RCC1 6	304..356		6/51 (12%)
		BTB_POZ_RCBTB1_CLLD7	350..466	CDD:349662	14/61 (23%)
		BACK_RCBTB1	466..531	CDD:350603
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910