DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and sergef

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_021329502.1	Gene:	sergef / 565673	ZFINID:	ZDB-GENE-061220-11	Length:	397	Species:	Danio rerio

Alignment Length:	370	Identity:	88/370 - (23%)
Similarity:	149/370 - (40%)	Gaps:	84/370 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 EEKYRYVASGPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTI-IPALEQLNIVQAAV 176
            ||:.|.|..|  ..|:.||:...:.|..|:|..|||||...:::....|. :|...:  :.|.:.
Zfish    44 EEQIRAVTGG--GGHSALISDSGELLVCGQNHKGQLGLCHTLEIMTFQTCPLPGFGR--VQQVSC 104

  Fly   177 GRHHTLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPINYRG--PPIIRIGCGAEFSVILDIK 239
            |...|:.||..|.|.|||.|..||  :|.:....:|..|:..:.  .|:..:..|...::.....
Zfish   105 GWDFTIILTGDGLVLACGSNAFGQ--LGGSAEKTHSAEPLLLKSFHEPVTSVAAGLRHALASTAS 167

  Fly   240 GSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFET------------SPKKVV--------LYIE 284
            |.::.:|      .|.::.||..:|...:..|..:            :.:||:        |.:.
Zfish   168 GCVYQWG------TGLSSHAKRMLNPQPVPSHLSSKEPCLVPGFAHVTTQKVIAGSAHCACLTVN 226

  Fly   285 -------KSKEGHV--------TPV-------DGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFG 327
                   .:|.|.:        .||       ...::.|...|..|.||.....||::||...:|
Zfish   227 GDVFLWGSNKHGQLISGSLFLPLPVALDRSMLQDERVSDVHSGWTHLVAQTESGRVFTWGRSNYG 291

  Fly   328 RLG---HAEPKDEMVPRLMK-------FFDTQGRGGRSVFCGSTFSLIVNELGLLFLFGQNK--K 380
            :||   |:..|.....||::       .|     |...:.|||..:|.|.. |.:|.:|.|:  .
Zfish   292 QLGQTNHSMEKQSCDERLVRSPVEVKALF-----GATQISCGSEHNLAVVG-GRVFSWGWNEHGM 350

  Fly   381 TGEANM----YPKPVQDLSGWNITDIGC-ANTSIMI----SADDT 416
            .|:.::    .|:|:..|:......||| |..|:.:    |::|:
Zfish   351 CGDGSLQDITQPQPIPALADAVALLIGCGAGHSMALCSLKSSEDS 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	12/45 (27%)
		RCC1_2	171..200	CDD:290274	11/28 (39%)
		RCC1	188..236	CDD:278826	13/49 (27%)
		RCC1	239..312	CDD:278826	18/114 (16%)
		RCC1	317..366	CDD:278826	17/58 (29%)
		RCC1	414..465	CDD:278826	1/3 (33%)
sergef	XP_021329502.1	RCC1	13..387	CDD:332518	86/360 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5530
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850