DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and hectd3

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001070627.2	Gene:	hectd3 / 563189	ZFINID:	ZDB-GENE-031118-179	Length:	854	Species:	Danio rerio

Alignment Length:	212	Identity:	47/212 - (22%)
Similarity:	70/212 - (33%)	Gaps:	79/212 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   331 HAEPKDEMVPRLMKFFDTQGRGGRSVF------CGSTFSLIVNELGLLFLFGQNKKTGEAN---- 385
            |.|..|.:||  ::..||..| .:.:|      | :.:..:|:....|.: |...|..||:
Zfish   138 HTEGGDRLVP--VESADTISR-QQQLFGYDHKPC-NRWEQVVDVENSLHM-GAKPKVAEADEAAV 197

  Fly   386 ---MYPKPV------QDLSGWNITDIG-----------CANTSIMISAD--------------DT 416
               .|..|.      :||..:....||           |. |||.:|:.              ||
Zfish   198 RKLRYVPPTWTFECDEDLVHYFYDHIGKEDENLGSVKQCV-TSIDVSSSSEDPSGGASCLTDGDT 261

  Fly   417 LIAWGASPTFGELGIGEFQKSSTVPKEVPKLDNIKIPQVTMGYSHTVLLVDTTHEATKQK----- 476
            ...|.:....|:..|....:..||   |.||               :|.||:|.:....|
Zfish   262 ETYWESDGMQGQHWIRLHMRRGTV---VNKL---------------ILTVDSTDDNYMPKRVTVY 308

  Fly   477 ------YEKMPEYTIDD 487
                  .:|..:.||||
Zfish   309 GGEGDNLKKYSDVTIDD 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826
		RCC1_2	171..200	CDD:290274
		RCC1	188..236	CDD:278826
		RCC1	239..312	CDD:278826
		RCC1	317..366	CDD:278826	10/40 (25%)
		RCC1	414..465	CDD:278826	10/64 (16%)
hectd3	NP_001070627.2	APC10-HECTD3	231..366	CDD:176487	25/114 (22%)
		HECTc	523..842	CDD:214523
		HECT	561..838	CDD:279026
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010