DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and rpgrb

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001299605.1	Gene:	rpgrb / 557752	ZFINID:	ZDB-GENE-081015-2	Length:	1413	Species:	Danio rerio

Alignment Length:	456	Identity:	110/456 - (24%)
Similarity:	168/456 - (36%)	Gaps:	162/456 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 FTEEKYRYVASGPSA---------------AHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKP 160
            ||..|.::..:.||.               .||.|:..:.|...||.|..|||||.....: .||
Zfish    16 FTFGKSKFADNAPSKFWLKNDVPLRISCGDEHTALVTENGKLFMFGSNNWGQLGLGTKTTV-NKP 79

  Fly   161 TIIPALEQLNIVQAAVGRHHTLFLTDTGTVYACGENKSGQCGVG--------------------- 204
            |.:.||:...:...|.||.|||..|..|.:||||.|..||.|:|
Zfish    80 TCVKALKSERVKLTACGRTHTLVFTSRGNLYACGGNNEGQLGLGDCNDRTSFHLVEFFNKQGPIK 144

  Fly   205 ------NTHA-------------------------NIYSPTPINYRGPPIIRIGCGAEFSVILDI 238
                  ||.|                         |..:|..::. |..:..:.||...|..:.:
Zfish   145 MLAAGSNTSAALTQDGRLYMWGDNSEGQIGLGKESNALTPQEVSV-GKRVFWVSCGYYHSAFVTV 208

  Fly   239 KGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFA 303
            .|:|:|||..:.|:||.:|:        ||:.|      ||        ...||.:.. ::|..|
Zfish   209 DGALYTFGEKDSGKLGLSTE--------KLANH------KV--------PQQVTDIPD-RVVQVA 250

  Fly   304 CGNNHTVAIDSKKRVYSWGFGGFGRLGHAE-PKDEMVPRLMKFFDTQGRGGR--SVFCGSTFSLI 365
            ||..||||: ::..|||:|.|.||:|||.. ..:..:||:::.|    |.||  ...||...:.:
Zfish   251 CGGGHTVAL-TENEVYSFGLGQFGQLGHGTFIFESRLPRVVEHF----RKGRVKHAACGENHTAL 310

  Fly   366 VNELGLLFLFGQNKKTGEANMYPKPVQDLSGWNITDIGCANTSIMISADDTLIAWGASPTFGELG 430
            :.:.|||:.||..:                                              .|:||
Zfish   311 ITDNGLLYTFGDGR----------------------------------------------HGKLG 329

  Fly   431 IGEFQKSSTV-PKEVPKLDNIKIPQVTMGYSHTVLLV---------------DTTHEATKQKYEK 479
            :||...::.. |...|:..:..:..||.|..|.::|.               |.|.:..::.|.:
Zfish   330 LGEENFTNQFKPTLCPRFLDYHVHSVTCGGCHMLVLAKPRTERPDDLILEEDDVTEDYLEKSYTE 394

  Fly   480 M 480
            :
Zfish   395 L 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	19/44 (43%)
		RCC1_2	171..200	CDD:290274	13/28 (46%)
		RCC1	188..236	CDD:278826	19/99 (19%)
		RCC1	239..312	CDD:278826	23/72 (32%)
		RCC1	317..366	CDD:278826	18/51 (35%)
		RCC1	414..465	CDD:278826	11/51 (22%)
rpgrb	NP_001299605.1	RCC1	54..102	CDD:278826	19/48 (40%)
		RCC1	107..156	CDD:278826	13/48 (27%)
		RCC1_2	143..172	CDD:290274	3/28 (11%)
		RCC1	159..206	CDD:278826	6/47 (13%)
		RCC1	209..259	CDD:278826	23/72 (32%)
		RCC1	261..311	CDD:278826	18/53 (34%)
		RCC1	314..365	CDD:278826	16/96 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820