DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and rcbtb1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001017352.2	Gene:	rcbtb1 / 550106	XenbaseID:	XB-GENE-987316	Length:	599	Species:	Xenopus tropicalis

Alignment Length:	349	Identity:	81/349 - (23%)
Similarity:	137/349 - (39%)	Gaps:	87/349 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 GPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTIIP-ALEQL---NIVQAAVGR-HHT 181
            |.:|...|....:.:...||.|.|..||...:     :.|||| .|:.|   .||..:.|. .|.
Frog    97 GSAANEAIYTTQNNEVFVFGMNSSNCLGTGDN-----QSTIIPRRLDVLCGKRIVDLSYGSGPHI 156

  Fly   182 LFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPI--NYRGPPIIRIGCGAEFSVILDIKGSLHT 244
            |...:.|.||:.|.|...|.|.||....: :|..:  ......:|::.||:..|:.|...|.:..
Frog   157 LVCNEDGEVYSWGHNGYSQLGNGNAIQGV-APVQVCMELLAKKVIQVACGSHHSMALTSDGEVFC 220

  Fly   245 FGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHT 309
            :|....||:|..|.|.            ::.|::|...::..           .:|..|.|.:.:
Frog   221 WGYNNCGQVGSGTTAN------------QSVPRRVSATLQSK-----------VVVSIAAGQSSS 262

  Fly   310 VAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVFCGSTFSLIVNELGLLFL 374
            :|:.....||.||:.|.|:||.....::::|                 |...|:..|..:.::
Frog   263 MAVTDNGHVYCWGYNGTGQLGIGNTGNQLMP-----------------CRLVFAHPVCIIQVV-- 308

  Fly   375 FGQNKKTGEANMYPKPVQDLSGWNITDIGCANTSIMISADDTLIAWGASPTFGELGIGEFQKSST 439
                                       :|.|:| :.:|....|.||||: :.|:||||. :.:.|
Frog   309 ---------------------------LGYAHT-LALSDQGVLYAWGAN-SHGQLGIGN-KSNQT 343

  Fly   440 VPKEVPKLDNIKIPQVTMGYSHTV 463
            .|.:|.  .|.::.:||..:|..:
Frog   344 APVKVG--TNERMVEVTACHSTNI 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	17/49 (35%)
		RCC1_2	171..200	CDD:290274	10/29 (34%)
		RCC1	188..236	CDD:278826	14/49 (29%)
		RCC1	239..312	CDD:278826	12/72 (17%)
		RCC1	317..366	CDD:278826	11/48 (23%)
		RCC1	414..465	CDD:278826	17/50 (34%)
rcbtb1	NP_001017352.2	RCC1	111..153	CDD:278826	15/46 (33%)
		RCC1	162..212	CDD:278826	14/50 (28%)
		RCC1	215..265	CDD:278826	12/72 (17%)
		RCC1	268..317	CDD:278826	15/95 (16%)
		RCC1_2	304..333	CDD:290274	9/59 (15%)
		RCC1	321..362	CDD:278826	16/44 (36%)
		BTB	428..532	CDD:279045
		BTB	439..535	CDD:197585
		SPOP_C_like	535..591	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010