DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9135 and CG8060

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_611117.2	Gene:	CG8060 / 36824	FlyBaseID:	FBgn0034113	Length:	1189	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	56/216 - (25%)
Similarity:	92/216 - (42%)	Gaps:	35/216 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 LGFGRNPSGQLGLSQDIKLAEKPTIIPALEQLN--IVQAAVGRHHTLFLTDTGTVYACGENKSGQ 200
            |.:|.|.:..||:..: :....|..:....:.|  :.|.|:|.:|:||....|.:||.|..|.|:
  Fly   149 LVWGSNKNYNLGIGNE-QNTNTPQAVDFFRKSNLWLEQVALGAYHSLFCDKKGHLYAVGHGKGGR 212

  Fly   201 CGVGNTHANIYSPTPINYR------GPPIIRIGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDA 259
            .|:|..::   .|.|...:      |..|..|....:.|::|..:..:...||....|||....|
  Fly   213 LGIGLENS---LPAPKRVKVSSKLSGDSIQCISVSRQHSLVLTHQSLVFACGLNTDHQLGVRDAA 274

  Fly   260 KYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDSKKRVYSWGFG 324
            :..           |..|:||...:|...      |.|:::  || :.|::|..| :.||.|| .
  Fly   275 EQL-----------TQFKEVVALRDKGAS------DLVRVI--AC-DQHSIAYGS-RCVYVWG-A 317

  Fly   325 GFGRLG-HAEPKDEMVPRLMK 344
            ..|:.| ::......||.|:|
  Fly   318 NQGQFGINSNTPSITVPTLIK 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	11/46 (24%)
		RCC1_2	171..200	CDD:290274	11/28 (39%)
		RCC1	188..236	CDD:278826	14/53 (26%)
		RCC1	239..312	CDD:278826	16/72 (22%)
		RCC1	317..366	CDD:278826	10/29 (34%)
		RCC1	414..465	CDD:278826
CG8060	NP_611117.2	ANK	<46..138	CDD:238125
		ANK repeat	56..87	CDD:293786
		Ank_4	57..111	CDD:290365
		ANK repeat	89..121	CDD:293786
		Ank_2	95..>138	CDD:289560
		RCC1	147..195	CDD:278826	11/46 (24%)
		RCC1	199..251	CDD:278826	14/54 (26%)
		BTB	547..>635	CDD:295341
		BTB	684..795	CDD:279045
		BTB	697..798	CDD:197585
		SPOP_C_like	798..>834	CDD:269810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900