DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9135 and Herc2

DIOPT Version :9

Sequence 1:NP_001285655.1 Gene:CG9135 / 33850 FlyBaseID:FBgn0031769 Length:487 Species:Drosophila melanogaster
Sequence 2:XP_006229362.1 Gene:Herc2 / 308669 RGDID:1307989 Length:4836 Species:Rattus norvegicus


Alignment Length:512 Identity:118/512 - (23%)
Similarity:190/512 - (37%) Gaps:160/512 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 LATLEKTPGQMLIAGMV---TWDLTGKRDRKNVTKVR----PNLYSFHRFTE----------EKY 116
            ||....|..|||.|.::   .|| :|.::..|....:    |.|...|||..          |..
  Rat   297 LAVQRGTLSQMLSAILLLLQLWD-SGAQETDNERSAQGTSAPLLPLLHRFQSILCSKDMPHTESD 360

  Fly   117 RYVASGP------------------------SAAHTILINMDRKA-------------------- 137
            .::.|||                        ..|..::.::||.|                    
  Rat   361 MHLLSGPLSPNESFLKYLTLPQDNELAIDLRQTAVVVMAHLDRLATPCMPPLCSSPTSHKGSLQE 425

  Fly   138 -LGFG-------RNPSG--------QLGLSQDIKLAEK----------------------PTIIP 164
             :|:|       .|..|        .||:.| :..|||                      |.::.
  Rat   426 VIGWGLIGWKYYANVIGPIQCEGLASLGVMQ-VACAEKRFLILSRNGRVYTQAYNSDMLAPQLVQ 489

  Fly   165 ALEQLNIVQAAV--GRHHTLFLTDTGTVYACGENKSGQCGVGNT----HANIYSPTPINYRGPPI 223
            .|...|||:.|.  ..||.|.|..||.||:.|....|:.|.|:|    ...:.|.......|..:
  Rat   490 GLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHGDTVPLEEPKVISAFSGKQAGKHV 554

  Fly   224 IRIGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKE 288
            :.|.||:.:|..:..:|.|:|:|...||:|||.                             |.|
  Rat   555 VHIACGSTYSAAITAEGELYTWGRGNYGRLGHG-----------------------------SSE 590

  Fly   289 GHVTP-----VDGVQIVDFACGNN--HTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFF 346
            ....|     :.|::::|.|||:.  .|:|:....:|:|||.|.:|:||.........|:|::  
  Rat   591 DEAIPMLVAGLKGLKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGKLGRGGSDGCKTPKLIE-- 653

  Fly   347 DTQGRGGRSVFCGSTFSLIVNELGLLFLFGQ--NKKTG----EANMYPKPVQDLSGWNITDIGCA 405
            ..|......|.|||.||:.:.:.|.::.:|:  |::.|    |...|||.::.|.|..:.|:...
  Rat   654 KLQDLDVIKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEEHVRYPKLLEGLQGKKVIDVAAG 718

  Fly   406 NTSIMISADDTLI-AWGASPT---FGELGIGEFQKSSTVPKEVPKLDNIKIPQVTMG 458
            :|..:...:|:.: :||::..   |..|.:     :...|..:|.||...|..:..|
  Rat   719 STHCLALTEDSEVHSWGSNDQCQHFDTLRV-----TKPEPTALPGLDTKHIVGIACG 770

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9135NP_001285655.1 RCC1 139..184 CDD:278826 19/83 (23%)
RCC1_2 171..200 CDD:290274 12/30 (40%)
RCC1 188..236 CDD:278826 14/51 (27%)
RCC1 239..312 CDD:278826 18/79 (23%)
RCC1 317..366 CDD:278826 17/48 (35%)
RCC1 414..465 CDD:278826 11/49 (22%)
Herc2XP_006229362.1 ATS1 <494..787 CDD:227511 82/313 (26%)
Cyt-b5 1212..1283 CDD:395121
MIB_HERC2 1871..1931 CDD:399589
UBA_HERC2 2461..2508 CDD:270585
Cul7 2555..2632 CDD:402903
SH3_15 2640..2697 CDD:408152
ZZ_HERC2 2707..2751 CDD:239084
APC10-HERC2 2766..2911 CDD:176485
ATS1 2957..3323 CDD:227511
ATS1 4025..4330 CDD:227511
HECTc 4423..4794 CDD:238033
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5184
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1062377at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.820

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