DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and Zzef1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_006246919.1	Gene:	Zzef1 / 287476	RGDID:	1311189	Length:	2965	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	58/296 - (19%)
Similarity:	100/296 - (33%)	Gaps:	65/296 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AGGNGAGPNKRRPKKKESDYEDEFSDESDDDGVQQQAAAANQMEVLIPHDDLDPPSKLPEDLLAT 71
            |||.|..|           ::|..:|.....|....||.......|:      .|::|.|...|.
  Rat    16 AGGEGWSP-----------HQDWAADSGATPGPGPAAAVLPSAAALL------EPARLREAAAAL 63

  Fly    72 LEKTPGQMLIA----GMVTW--DLTGKRDRKNVT--------KVRPNLYSFHRFTEEKYRYVASG 122
            ....|.:.|::    .::.|  :..| |..::||        :.|....|..:|.|...::.|.|
  Rat    64 RPAPPCESLVSRHHGALLRWLEERLG-RGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEG 127

  Fly   123 PSA--AHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTIIPA-LEQLNIVQAAVGRHHTLFL 184
            ...  |..:|..:...:   |.|..|:  ||..|:..:..:::|. ::..:..:..:|.|.::.|
  Rat   128 DGTVDAENMLEALKNSS---GANLQGE--LSHVIRQLQACSLVPGFIDIFSESKEGLGTHSSMIL 187

  Fly   185 TDTGTVYACGENKSGQCGVGNTHANIYSPTPINYRGPPII---RIGCGAEFSVILDIKGSLHTFG 246
            .                   ..|.|..|...|.|   |::   ...|....||:.|....|....
  Rat   188 R-------------------FLHRNRVSSMVIPY---PMLDHCNNMCTMRSSVLKDSLDQLLQKE 230

  Fly   247 LPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLY 282
            ....|.|..:.:.....:..|...:.|||.....:|
  Rat   231 KESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIY 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	9/45 (20%)
		RCC1_2	171..200	CDD:290274	3/28 (11%)
		RCC1	188..236	CDD:278826	9/50 (18%)
		RCC1	239..312	CDD:278826	8/44 (18%)
		RCC1	317..366	CDD:278826
		RCC1	414..465	CDD:278826
Zzef1	XP_006246919.1	EFh	<94..141	CDD:238008	10/46 (22%)
		APC10-ZZEF1	250..380	CDD:176488	5/17 (29%)
		CUB	<1119..1189	CDD:294042
		ZZ_EF	1779..1826	CDD:239083
		ZZ	1828..1875	CDD:239069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900