DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and nekl-1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001293320.1	Gene:	nekl-1 / 189769	WormBaseID:	WBGene00021461	Length:	983	Species:	Caenorhabditis elegans

Alignment Length:	404	Identity:	98/404 - (24%)
Similarity:	153/404 - (37%)	Gaps:	115/404 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 PSAAHTILINMDRKALGFGRNPSGQLGLS------QDIKLAEKPTI----IPAL-EQLNIVQAAV 176
            |||...  :.|.|.:....|:.||.:..|      .|:.:   |||    ||.| .:::|.|.|:
Worm   415 PSAPQA--LKMLRPSENRHRHTSGSMRSSVSFTTLYDLHV---PTITLSSIPDLPSRISIKQVAL 474

  Fly   177 GRHHTLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPINYRGPPIIRIGCGAEFSVILDIKGS 241
            .:.||:.||:...::..|:|..||.|.|............:.:|..|..:|.|..||||...:|:
Worm   475 SKTHTMVLTNDNELFGFGDNSCGQLGFGKFSKMENGRLVESLKGRDIQSVGVGNYFSVICCDRGT 539

  Fly   242 LHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVTPVDGVQIVDFACGN 306
            |.|||..:  .||...|||              ...|.:|..:..:|         .|.|..||:
Worm   540 LLTFGTAK--NLGLGKDAK--------------DSAKPMLLEQLLRE---------NIKDIYCGH 579

  Fly   307 NHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFD------------TQGRGGRSVFCG 359
            :|.||:........||...:|:||        :|.|..||.            ..|:.|:..
Worm   580 DHVVAVLESGECLGWGSNQYGQLG--------LPTLEHFFAPTKIPMPSNKKIVYGKAGKDA--- 633

  Fly   360 STFSLIVNELGLLFLFGQNKKTGEANM--------------------------YPKPVQDLSGWN 398
               ::::::.|.|...|.||. .:.|:                          :|:.|.|.|
Worm   634 ---TMLLSDDGSLIAMGSNKH-NKLNLTQRVGFFTKEKKTPNDYVNKPTILQGFPERVVDFS--- 691

  Fly   399 ITDIGCANTSIMISADDTLIAWGASPTFG-----ELGIGEFQKSST-VPKEVPKLDNIKIPQVTM 457
               :|..::.:::.:...:|       ||     |||:|..||.:. ..|.|..|.:.....|..
Worm   692 ---VGSYHSGVILESGQVMI-------FGRNDNTELGLGNSQKMAVRCVKPVKSLLHHACTHVLC 746

  Fly   458 GYSHTVLLVDTTHE 471
            |...|  ||.||.:
Worm   747 GDGFT--LVSTTEQ 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	16/55 (29%)
		RCC1_2	171..200	CDD:290274	9/28 (32%)
		RCC1	188..236	CDD:278826	13/47 (28%)
		RCC1	239..312	CDD:278826	19/72 (26%)
		RCC1	317..366	CDD:278826	11/60 (18%)
		RCC1	414..465	CDD:278826	15/56 (27%)
nekl-1	NP_001293320.1	STKc_Nek	170..423	CDD:270855	3/9 (33%)
nekl-1	NP_001293320.1	ATS1	449..764	CDD:227511	89/368 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010