DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and Nek8

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_006532246.1	Gene:	Nek8 / 140859	MGIID:	1890646	Length:	702	Species:	Mus musculus

Alignment Length:	267	Identity:	70/267 - (26%)
Similarity:	116/267 - (43%)	Gaps:	52/267 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 YRYVASGPSAAHTILINMDRKALGFGRNPSGQLGLS--QDIKLAEKPTIIPALEQLNIVQAAVGR 178
            |..|.....|:|.:.::.|.:...:||...|:|||.  :.....::..:.|..|...:|   .|.
Mouse   449 YEMVQVACGASHVLALSTDGELFAWGRGDGGRLGLGTRESHNCPQQVPVAPGQEAQRVV---CGI 510

  Fly   179 HHTLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPINYR-------------GP----PIIRI 226
            ..::.||..|.|.|||.|:..:.|:  .|.:: ...|:.|:             .|    |::.:
Mouse   511 DSSMILTSPGRVLACGSNRFNKLGL--DHLSL-DEEPVPYQQVEEALSFTPLGSAPLDQEPLLCV 572

  Fly   227 GCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHV 291
            ..|...|..:...|..:|||..::||||                   ||.::|     ......|
Mouse   573 DLGTAHSAAITASGDCYTFGSNQHGQLG-------------------TSSRRV-----SRAPCRV 613

  Fly   292 TPVDGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSV 356
            ..::|:::|..|||:..|||:.::..|||||.|..||||..: :|..:||.::..:|......||
Mouse   614 QGLEGIKMVMVACGDAFTVAVGAEGEVYSWGKGTRGRLGRRD-EDAGLPRPVQLDETHPYMVTSV 677

  Fly   357 FC--GST 361
            .|  |:|
Mouse   678 SCCHGNT 684

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	10/46 (22%)
		RCC1_2	171..200	CDD:290274	10/28 (36%)
		RCC1	188..236	CDD:278826	14/64 (22%)
		RCC1	239..312	CDD:278826	19/72 (26%)
		RCC1	317..366	CDD:278826	19/47 (40%)
		RCC1	414..465	CDD:278826
Nek8	XP_006532246.1	STKc_Nek8	3..258	CDD:270859
Nek8	XP_006532246.1	ATS1	318..663	CDD:227511	63/244 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010