Protein Alignment CG9135 and Rcc2

DIOPT Version :10

• Sequence 1: NP_608985.1
• Gene: CG9135 / 33850
• FlyBaseID: FBgn0031769
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_776292.1
• Gene: Rcc2 / 108911
• MGIID: 1919784
• Length: 520
• Species: Mus musculus
• Alignment Length: 518
• Identity: 230/518 - (44%)
• Similarity: 308/518 - (59%)
• Gaps: 42/518 - (8%)

  Fly     5 RKAG--------GNG---AGPNKR-RPKKKESDYEDEFSDES------DDDGVQQQAAAANQMEV 51
            ||.|        |||   |||.:| .|..::.:..:..|..|      |:||.:...|.......
Mouse     3 RKKGAAWEEPSSGNGTARAGPRRRGGPAGRKRERPERCSSSSGGGSSGDEDGPELDGAPGGGKRT 67

  Fly    52 LIPHDD---------LDPPSKLPEDLLATLEKTPGQMLIAGMVTWDLTGKRDRKNVTK------- 100
            ..|...         :..|....|.:.....|..||:||.|...|||.|   ||.|.|
Mouse    68 ARPATAGKAAGAAAIITEPEHTKERVKLEGSKCKGQLLIFGATNWDLIG---RKEVPKQQAAYRN 129

  Fly   101 VRPNLYSFHRF---TEEKYRYVASGPSAAHTILINMDRKALGFGRNPSGQLGLSQDIKLAEKPTI 162
            :..||:..||:   :..:.|.|.||..|||::||..:.|...:|||..|||| ..|.|..|.|.:
Mouse   130 LGQNLWGPHRYGCLSGVRVRTVVSGSCAAHSLLITTEGKLWSWGRNEKGQLG-HGDTKRVEAPRL 193

  Fly   163 IPALEQLNIVQAAVGRHHTLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPINYRGPPIIRIG 227
            |.||....||.||.||:|||.|||||:|:|.||||.||.|:||....:.||..|.|.|.||.::.
Mouse   194 IEALSHEAIVLAACGRNHTLALTDTGSVFAFGENKMGQLGLGNQTDAVPSPAQIMYNGQPITKMA 258

  Fly   228 CGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGHVT 292
            ||||||:::|.||:|::||.|||||||||:|.|:...|.::.:..|..|::|.::|||:|:|.:.
Mouse   259 CGAEFSMLMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQIL 323

  Fly   293 PVDGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGRSVF 357
            ||..|.:.|.|||.|||:.:||:|||:||||||:|||||||.||||||||:|.||..|||...::
Mouse   324 PVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRLGHAEQKDEMVPRLVKLFDFPGRGATQIY 388

  Fly   358 CGSTFSLIVNELGLLFLFGQNKKTGEANMYPKPVQDLSGWNITDIGCANTSIMISADDTLIAWGA 422
            .|.|.|..|:|:|.||.:|....:.|:.||||.||||.||.|..:.|..:||:::||::.|:||.
Mouse   389 AGYTCSFAVSEVGGLFFWGATNTSRESTMYPKAVQDLCGWRIRSLACGKSSIIVAADESTISWGP 453

  Fly   423 SPTFGELGIGEFQ-KSSTVPKEVPKLDNIKIPQVTMGYSHTVLLVDTTHEATKQKYEKMPEYT 484
            ||||||||.|:.: ||||..:||..||.|...||.|||||::::.....||.|:|.:::||||
Mouse   454 SPTFGELGYGDHKPKSSTAAQEVKTLDGIFSEQVAMGYSHSLVIARDESEAEKEKLQRLPEYT 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_608985.1	ATS1	119..469	CDD:444065	183/350 (52%)
Rcc2	NP_776292.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..78		18/74 (24%)
		RCC1 1	101..163		24/64 (38%)
		ATS1	149..500	CDD:444065	184/351 (52%)
		RCC1 2	166..217		25/51 (49%)
		RCC1 3	219..269		25/49 (51%)
		RCC1 4	271..345		34/73 (47%)
		Required for interaction with RAC1. /evidence=ECO:0000250|UniProtKB:Q9P258	316..323		3/6 (50%)
		RCC1 5	346..399		34/52 (65%)
		RCC1 6	401..445		19/43 (44%)
		RCC1 7	446..499		28/52 (54%)