DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and herc1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	XP_017947876.1	Gene:	herc1 / 100493988	XenbaseID:	XB-GENE-1002062	Length:	4854	Species:	Xenopus tropicalis

Alignment Length:	375	Identity:	105/375 - (28%)
Similarity:	176/375 - (46%)	Gaps:	55/375 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 TEEKYRYVASGP--SAAHTI--------LINMDRKALGFGRNPSGQLGL--SQDIKLAEKPTIIP 164
            |:||.......|  |.|.||        :|:.|......|:...|:|||  |.:....:|.|..|
Frog   389 TQEKILQPKLAPCFSDAQTIEAGQYCTFVISTDGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEP 453

  Fly   165 --ALEQLNIVQAAVGRHHTLFLTDTGTVYACGENKSGQCGVGNTHANIYSPTPI--NYRGPPIIR 225
              ::::::..:.:.|  |||..|..|.|::.|:...|:.|.||:....| |..|  ..:|..::.
Frog   454 HRSIKKVSSSKGSDG--HTLAFTTEGEVFSWGDGDYGKLGHGNSSTQKY-PKLIQGTLQGKVVVC 515

  Fly   226 IGCGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVLYIEKSKEGH 290
            :..|...|..:...|.|:|:|..::|:|||.       ::|  |.:..|..|.:      |..|.
Frog   516 VSAGYRHSAAVTEDGELYTWGEGDFGRLGHG-------DSN--SRNIPTLVKDI------SNVGE 565

  Fly   291 VTPVDGVQIVDFACGNNHTVAIDSKKR-VYSWGFGGFGRLGHAEPKDEMVPRLMKFFDTQGRGGR 354
            |           :||::||:|:....| |:|:|.|..|:|||.:......|::::..  ||...|
Frog   566 V-----------SCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTNRVYKPKVVEAL--QGMFTR 617

  Fly   355 SVFCGSTFSLIVNELGLLFLFGQNKKTG----EAN-MYPKPVQDLSGWNITDIGCANT-SIMISA 413
            .|..||..||.:...|.::.:|.....|    ||. :.||.:::|:...|.||...:: .:.:|.
Frog   618 KVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIEELAATRIVDISIGDSHCLALSH 682

  Fly   414 DDTLIAWGASPTFGELGIGEFQKSSTVPKEVPKLDNIKIPQVTMGYSHTV 463
            |:.:.||| :.:.|:.|.|......|.||:|..||.:.|.|::.|.||::
Frog   683 DNEVYAWG-NNSMGQCGQGNSTGPITKPKKVSGLDGVAIQQISAGTSHSL 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	13/48 (27%)
		RCC1_2	171..200	CDD:290274	8/28 (29%)
		RCC1	188..236	CDD:278826	13/49 (27%)
		RCC1	239..312	CDD:278826	19/72 (26%)
		RCC1	317..366	CDD:278826	18/49 (37%)
		RCC1	414..465	CDD:278826	18/50 (36%)
herc1	XP_017947876.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920