DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9135 and Rcc1

DIOPT Version :9

Sequence 1:	NP_001285655.1	Gene:	CG9135 / 33850	FlyBaseID:	FBgn0031769	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_001184011.1	Gene:	Rcc1 / 100088	MGIID:	1913989	Length:	434	Species:	Mus musculus

Alignment Length:	382	Identity:	100/382 - (26%)
Similarity:	155/382 - (40%)	Gaps:	112/382 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 EEKYRYVASGPSAAHTILINMDRKALGFG--RNPSGQLGLSQDIKLAEKPTIIPALEQLN--IVQ 173
            :||...|::|.|  ||..:..|.:...:|  |:.:|.:||.:.:    |.:::|...||:  :|:
Mouse   131 QEKVVQVSAGDS--HTAALTEDGRVFLWGSFRDNNGVIGLLEPM----KKSMVPVQVQLDAPVVK 189

  Fly   174 AAVGRHHTLFLTDTGTVY--ACGE------------NKSGQCGVGNTHANIYSPTPI-----NYR 219
            .|.|..|.:.||:.|.:|  .|||            |:.|:.|:|    .:..|..:     ..|
Mouse   190 VASGNDHLVMLTNDGDLYTLGCGEQGQLGRVPELFANRGGRQGLG----RLLVPRCVLLKSRGTR 250

  Fly   220 GPPIIRIG---CGAEFSVILDIKGSLHTFGLPEYGQLGHNTDAKYFVNANKLSFHFETSPKKVVL 281
            |.  :|..   |||.|:..:..:|.::.|||..|.|||.......|:..|..||...|
Mouse   251 GR--VRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPGTGSCFIPQNLTSFKNST------- 306

  Fly   282 YIEKSKEGHVTPVDGVQIVDFACGNNHTVAIDSKKRVYSWGFGGFGRLGHAEPKDE-MVPRLMKF 345
               ||..|            |:.|.:|||.:||:.:.||.|...:||||..|..:| .:|.|:..
Mouse   307 ---KSWVG------------FSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISR 356

  Fly   346 FDTQGRGGRSVFCGSTFSLIVNELGLLFLFGQNKKTGEANMYPKPVQDLSGWNITDIGCANTSIM 410
            .....    ||.||::                                        :|.|
Mouse   357 LPVVS----SVACGAS----------------------------------------VGYA----- 372

  Fly   411 ISADDTLIAWGASPTFGELGIGEFQKS-STVPKEVPKLDNIKIPQVTMGYSHTVLLV 466
            :|.|..:.|||....: :||.|:.:.: |.|.....:|:|..:..|:.|..||||||
Mouse   373 VSKDGRVFAWGMGTNY-QLGTGQDEDAWSPVEMTGKQLENRVVLTVSSGGQHTVLLV 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9135	NP_001285655.1	RCC1	139..184	CDD:278826	13/48 (27%)
		RCC1_2	171..200	CDD:290274	12/42 (29%)
		RCC1	188..236	CDD:278826	17/69 (25%)
		RCC1	239..312	CDD:278826	21/72 (29%)
		RCC1	317..366	CDD:278826	15/49 (31%)
		RCC1	414..465	CDD:278826	16/51 (31%)
Rcc1	NP_001184011.1	RCC1	48..95	CDD:278826
		RCC1	98..147	CDD:278826	7/17 (41%)
		RCC1	150..200	CDD:278826	14/53 (26%)
		RCC1_2	187..216	CDD:290274	11/28 (39%)
		RCC1	203..268	CDD:278826	17/70 (24%)
		RCC1	271..322	CDD:278826	21/72 (29%)
		RCC1	325..368	CDD:278826	15/46 (33%)
		RCC1	376..427	CDD:278826	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910