DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment IPIP and Pheta2

DIOPT Version :9

Sequence 1:	NP_001137795.2	Gene:	IPIP / 33849	FlyBaseID:	FBgn0031768	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001123983.1	Gene:	Pheta2 / 688685	RGDID:	1586415	Length:	259	Species:	Rattus norvegicus

Alignment Length:	196	Identity:	75/196 - (38%)
Similarity:	106/196 - (54%)	Gaps:	30/196 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKINEKNLYVFART-PPFDMEGFLNKRG-----EVNKAFQRRY-FVLKGNLLFYFESRLDKEPLG 58
            ||:|::::..:|.: .|.|..|||...|     .......||| |||||||||.||||..:.||.
  Rat     1 MKLNKRSVAHYALSDSPADHTGFLRSWGGPGSPPTPSGTGRRYWFVLKGNLLFSFESRESRVPLS 65

  Fly    59 LIIVEGCTIELSNE--VDNYCFEIAFN--GNRTYILAAENQDSMETWMKALTCAGYEYKRIILAE 119
            |:::||||:||:..  .:.:.|.|.|:  |.|.::|||:.|.:.|.|:|||:.|.:.|.|:::.|
  Rat    66 LVVLEGCTVELAEAPVPEEFAFAIRFDAPGVRPHLLAADGQAAQEAWVKALSRASFGYMRLVVRE 130

  Fly   120 LKRQLQEMEDARNKMLGSALD--GPQNASES-AKPRPPPRRTNPFNRPAPP-----PPDSSLRGG 176
            |:.|||   |||..:   ||.  .||.|..| :|.:.|..|.     |.|.     |.|.:..|.
  Rat   131 LESQLQ---DARQSL---ALHRCAPQRAVASRSKSQAPDHRA-----PGPENGHFLPRDGNSMGT 184

  Fly   177 V 177
            |
  Rat   185 V 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IPIP	NP_001137795.2	PH_Ses	11..127	CDD:270105	54/126 (43%)
IPIP	NP_001137795.2	PH	19..105	CDD:278594	41/95 (43%)
Pheta2	NP_001123983.1	PH-like	11..138	CDD:302622	54/129 (42%)
Pheta2	NP_001123983.1	PH	20..120	CDD:278594	43/99 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7287
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4610
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003195
OrthoInspector	1	1.000	-	-		otm45324
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22902
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3662
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.060