DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment IPIP and pheta2

DIOPT Version :9

Sequence 1:	NP_001137795.2	Gene:	IPIP / 33849	FlyBaseID:	FBgn0031768	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	XP_004913853.1	Gene:	pheta2 / 100488560	XenbaseID:	XB-GENE-985681	Length:	256	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	83/216 - (38%)
Similarity:	119/216 - (55%)	Gaps:	30/216 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKINEKNLYVFART-PPFDMEGFLNKRGEVNKAFQRRYFVLKGNLLFYFESRLDKEPLGLIIVEG 64
            ||:||:::..:|.: .|.|..|:|.|||..:.|:|:|:||||||||||||.:.:|||:|::::||
Frog     1 MKLNERSMAHYATSGSPADCTGYLYKRGVKHTAYQKRWFVLKGNLLFYFEEQGNKEPVGVVVLEG 65

  Fly    65 CTIEL--SNEVDNYCFEIAFNGNRTYILAAENQDSMETWMKALTCAGYEYKRIILAELKRQLQEM 127
            |.|||  |||...:|......|:|:||||||.|:.||.|:|||:.|.::|.|:::.||:|||:.|
Frog    66 CAIELCHSNEEHAFCVRFDGPGSRSYILAAETQEEMECWVKALSRASFDYMRLVVRELERQLELM 130

  Fly   128 EDARNKMLGSALDGPQNASESAK---PRPP--------PRRTN----------PFNRPAPPPPDS 171
            :....:.......|...|....|   .|||        |..||          ....|.|||...
Frog   131 QKTSIRRKPGRHRGRSRAVSRTKWENSRPPELCNGFLHPEDTNLETHTRVSGSSIPPPLPPPLPP 195

  Fly   172 SLRGGVVMSPLPFINGYFGSS 192
            ..||..      ::||...:|
Frog   196 RRRGAA------WVNGASSAS 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
IPIP	NP_001137795.2	PH_Ses	11..127	CDD:270105	60/118 (51%)
IPIP	NP_001137795.2	PH	19..105	CDD:278594	47/87 (54%)
pheta2	XP_004913853.1	PH_Ses	11..130	CDD:270105	60/118 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6762
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4438
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003195
OrthoInspector	1	1.000	-	-		otm48394
Panther	1	1.100	-	-	LDO	PTHR22902
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4038
SonicParanoid	1	1.000	-	-		X3662
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.180