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Protein Alignment mtm and MTMR7

DIOPT Version :9

Sequence 1:	NP_001285651.1	Gene:	mtm / 33845	FlyBaseID:	FBgn0025742	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_004677.3	Gene:	MTMR7 / 9108	HGNCID:	7454	Length:	660	Species:	Homo sapiens

Alignment Length:	516	Identity:	203/516 - (39%)
Similarity:	288/516 - (55%)	Gaps:	50/516 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 IFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWD------G 185
            |.||:.:.::....|:... ..|:..|...|.|:.|. .|:.|:.        |...|      |
Human    72 IRCKNFQIIQLIIPQERDC-HDVYISLIRLARPVKYE-ELYCFSF--------NPMLDKEEREQG 126

  Fly   186 WAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVL 250
            |.:.:...|..|:|:||..|:.:.:|..|.:|||||....|||:|:...:...::||||.|.|||
Human   127 WVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVL 191

  Fly   251 SWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGG 315
            |:......|:|.|.||||.|.|. |..:||..|..|.:||..||.:.::|.||..||:||:|.|.
Human   192 SYYYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGK 255

  Fly   316 GYESEDAYKNVEINFLDIHNIHVMRESLRKVKEAC---FPTTDDSKWQTAIDNTLWLKHIRCILA 377
            |||:||.|.|::..|:.|.||||||.||:|:.|.|   .|:..|..|  .::|:.||:||:.|:.
Human   256 GYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWLRHIKAIMD 318

  Fly   378 GAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQ 442
            ..:.|...|.....||:||||||||||||:.:::.|||||||||::||.|||||:|:||||||..
Human   319 AGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNH 383

  Fly   443 RIGH--GDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTE 505
            |.|:  ||.|    :.|||..|||:.|||:.:||..||||||.|||.|..|:|||:||.||||::
Human   384 RYGNLDGDPK----EISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQ 444

  Fly   506 AERVAEDLKHKTTSLWTHINSSLDQYLNPLF---PSFTHGA-ELVLRPIASVRSVRLWKGLYCRW 566
            .||....::.:|.|||.|:..:...||||||   .|.|.|. .|...|...:  .:.|.|:|.|:
Human   445 KERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTTPCNFM--YKFWSGMYNRF 507

  Fly   567 NPG----------LCAPQHGCQRTRELLSKQDQLFKLVNELRLKSNNRSNSMQTTTRLASP 617
            ..|          |.|.:...|:..|.|...::..:.:.:::|      |..:..::.:.|
Human   508 EKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQL------NCTKVKSKQSEP 562

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.