Protein Alignment mtm and Mtmr3

DIOPT Version :9

• Sequence 1: NP_001285651.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_006514908.1
• Gene: Mtmr3 / 74302
• MGIID: 1921552
• Length: 1205
• Species: Mus musculus
• Alignment Length: 598
• Identity: 206/598 - (34%)
• Similarity: 296/598 - (49%)
• Gaps: 108/598 - (18%)

  Fly    46 PFGYLEGEEDQDQKNDVTYVCPYRGPVFGA-LTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARV 109
            ||..|.||..:           |.|....| :.::||||:     ::.:|.  :|:|||.:|..|
Mouse    33 PFLELHGESTE-----------YVGRAEEAIIALSNYRLH-----IKFKES--LVNVPLQLIESV 79

  Fly   110 EKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQ------ANAF-PLSYSGRLF 167
            |        ..:.:.:.:.|||.:.:|        .:...||:.|      .||. |......||
Mouse    80 E--------CRDIFQLHLTCKDCKVIR--------CQFPTFEQCQDWLKRLNNAIRPPGKIEDLF 128

  Fly   168 AFA--------HAAANSVNGNGGWDGWAVYEPLA-ELRRLGVP-NDMWRATKLNESYAICDSYPA 222
            :||        :|:....:|:....|..|..... |:.|:|.. |:.||.:.:||.|.:|.|||.
Mouse   129 SFAYHAWCMEVYASEKEQHGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQ 193

  Fly   223 VWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIM 287
            ...||...:|..|..||.|||..|:|.:.:.:....|.|.||.||.|...|.||:|||..:..:.
Mouse   194 ELIVPAWITDKELESVAGFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVA 258

  Fly   288 EANA---------------------------------------------QSDKLTIMDARPSANA 307
            .|.|                                             |..||.|:|||..|.|
Mouse   259 RACASDSQSSISKVSTRNSCRDFPNAGDLSDVEFDSSLSNTSGAESLALQPQKLLILDARSYAAA 323

  Fly   308 IANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHI 372
            :||:|||||.|..:.|.|.|:.|:.:.|||.:|.|.:.::..|....|...|.:|:::|.||.|:
Mouse   324 VANRAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHL 388

  Fly   373 RCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFG 437
            ..:|..|:.:|..|:.....|:||||||||||.|:.||:.|||||:|||:.||:||:|.|||.||
Mouse   389 SVLLKSALLVVHAVDRDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFG 453

  Fly   438 HKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLC 502
            |||..|.|||::.....:|.|||||::|.|.|:.:||..:|||||.||:.:|.|.|||.||||||
Mouse   454 HKFADRCGHGEDSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLC 518

  Fly   503 NTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLY--CR 565
            |...||..:..:.:|.|:|:.:.:....:.|.|:.|   .:|.||.|:..||::.||..:|  |.
Mouse   519 NNAKERGEKQTQERTCSVWSLLRAGNKAFKNLLYSS---QSEAVLYPVCHVRNLMLWSAVYLPCP 580

  Fly   566 WNPGL-----CAP 573
             :|..     |||
Mouse   581 -SPSTPTDDSCAP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_001285651.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	24/109 (22%)
		Myotub-related	184..509	CDD:399535	149/371 (40%)
Mtmr3	XP_006514908.1	PH-GRAM_MTMR3	23..116	CDD:270149	27/116 (23%)
		PTP-MTMR3	169..485	CDD:350434	122/315 (39%)
		FYVE_MTMR3	1113..1182	CDD:277271

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750