Protein Alignment mtm and mtmr1a

DIOPT Version :9

• Sequence 1: NP_001285651.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_009301334.1
• Gene: mtmr1a / 553750
• ZFINID: ZDB-GENE-050522-518
• Length: 699
• Species: Danio rerio
• Alignment Length: 651
• Identity: 313/651 - (48%)
• Similarity: 429/651 - (65%)
• Gaps: 54/651 - (8%)

  Fly     7 LADKLASKTASSNSLDSSSKSSSLGSK-------------HGGGENG------------------ 40
            :|..::|:..|....:|..:.|.:|.|             ...||:|
Zfish    56 IAATISSQITSGVPSESIHRESKIGKKIDTRVSKRPNFRSQDSGEDGCQFDSDCELPSHTSQVFR 120

  Fly    41 -ILRDTPFG---YLEGEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDV 101
             :.|..|..   .:.||..:....||.|:||:.|.|.|.||||:|:|||.||   :::.|.::||
Zfish   121 DVRRPAPMDEVPLVPGETIKTTVKDVMYICPFTGAVTGTLTITDYKLYFVSL---ERDAPFILDV 182

  Fly   102 PLGVIARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRL 166
            .||.|:|:|.| ...|.|||:.|:||.|||||:.|||:|::..|:..:.|.|...|||||....|
Zfish   183 NLGAISRLETI-SVQSLGENTSGMEIVCKDMRSPRFAYKKEEQSKLEILETLTKYAFPLSNELSL 246

  Fly   167 FAFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAAS 231
            |||.:......      |||.||:|:||.:|:|:||:.|..:|:|.:|.:||:|||:...|.:..
Zfish   247 FAFQYKEQFPE------DGWKVYDPVAEYKRMGLPNESWSISKINSNYEVCDTYPALLVTPTSIK 305

  Fly   232 DDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKL 296
            :|.:||||.||.:.|:|||||::|.|||||.|||||:||.:.:|..:||.||..||:|||||.||
Zfish   306 EDEIRRVASFRVKHRIPVLSWIHPETQATIVRCSQPMVGPTDRRCKEDEHYLQTIMDANAQSHKL 370

  Fly   297 TIMDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQT 361
            .|.|||.:..|..:|.|.||||:|:.|.|:|:|||:|.|||||||||||:||..:||.::.:|.:
Zfish   371 AIFDARQNTVAHNHKTKDGGYENENFYPNMELNFLEIPNIHVMRESLRKLKEVVYPTIEEQRWHS 435

  Fly   362 AIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFE 426
            |||.|.||::||.:|||||||.||||:..:|||||||||||||||||:||||:||.:|||:|||:
Zfish   436 AIDATHWLEYIRLLLAGAVRIADKVESSKSSVVVHCSDGWDRTAQLTSLSMLMLDSYYRTLRGFQ 500

  Fly   427 VLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDH 491
            ||:||||:||||||..||||||..|::::|||:|:||||.|||:.:||.:||||||.|||||:|:
Zfish   501 VLLEKEWISFGHKFAARIGHGDENHANSERSPLFVQFIDCVWQMMRQFPSAFEFNELFLITILDY 565

  Fly   492 LYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSV 556
            ||||.|||||.|:|.|||.:::..||.|||::|||..:.:.||.:..:.:.   ||.|:||:|.:
Zfish   566 LYSCLFGTFLYNSEQERVEKEVNRKTVSLWSYINSQSEDFTNPFYVDYENH---VLYPLASLRHL 627

  Fly   557 RLWKGLYCRWNPGL--CAPQHGCQRTRELLSKQDQLFKLVNELRLKSNNRSNSMQTTTRLA-SPM 618
            .||.|.|.||||.:  ..|.|  |..:|||..:.:|.:.|.||: |..:.|.|:.:::..| ||.
Zfish   628 ELWVGYYVRWNPRMRPQMPVH--QNLKELLYLRAELQRKVEELQ-KDVSSSRSVSSSSEHAYSPS 689

  Fly   619 H 619
            |
Zfish   690 H 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_001285651.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	47/101 (47%)
		Myotub-related	184..509	CDD:399535	201/324 (62%)
mtmr1a	XP_009301334.1	PH-GRAM_MTMR1	140..239	CDD:270165	47/102 (46%)
		Myotub-related	246..581	CDD:284109	204/340 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590814
Domainoid	1	1.000	469	1.000	Domainoid score	I432
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	655	1.000	Inparanoid score	I758
OMA	1	1.010	-	-		QHG58725
OrthoDB	1	1.010	-	-		D319276at33208
OrthoFinder	1	1.000	-	-		FOG0000303
OrthoInspector	1	1.000	-	-		otm24644
orthoMCL	1	0.900	-	-		OOG6_101490
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X213
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910