Protein Alignment mtm and mtm1

DIOPT Version :10

• Sequence 1: NP_523489.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001015828.1
• Gene: mtm1 / 548545
• XenbaseID: XB-GENE-1002030
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 328/603 - (54%)
• Similarity: 428/603 - (70%)
• Gaps: 23/603 - (3%)

  Fly    17 SSNSLDSSSKSSSLGSKHGGGENGILRDTPFGYLEGEEDQDQKNDVTYVCPYRGPVFGALTITNY 81
            :||||::|.:.|.     |.|.|....| ....|.||.....| ||.|:||:.|||.|.:.:|||
 Frog    10 NSNSLENSLRRSP-----GDGMNHEQND-EIPCLPGEALITDK-DVIYMCPFYGPVKGRIHVTNY 67

  Fly    82 RLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSR 146
            :|||:.   .:.||.:...||||||||:||:|||:||||||||::|.||||||||||.||:.|||
 Frog    68 KLYFKG---EEMEPLISFSVPLGVIARIEKMGGASSRGENSYGLDITCKDMRNLRFALKQEVHSR 129

  Fly   147 RTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPNDMWRATKLN 211
            :.:||.|...|||||:...||||.:......|      |||||:.:.|.||.|:||..||.|.:|
 Frog   130 KQIFEDLTKYAFPLSHGLLLFAFQNEEKFPEN------GWAVYDAMTEFRRQGLPNGQWRITFIN 188

  Fly   212 ESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRN 276
            ::|.:||:||.:..||.:||::.|::||.||||.|:|||||::|..|:.|.||||||||:|||||
 Frog   189 KNYELCDTYPPLLVVPYSASEEDLKKVAAFRSRNRIPVLSWLHPENQSAIMRCSQPLVGMSGKRN 253

  Fly   277 SDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRE 341
            .|||.||..|.:.|.|:.||||.||||:.||:||||.||||||||||.|.|:.||||||||||||
 Frog   254 KDDERYLDIIRDTNGQTSKLTIYDARPNVNAVANKATGGGYESEDAYPNAELVFLDIHNIHVMRE 318

  Fly   342 SLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQ 406
            ||:|:|:..:|..::|.|.:::::|.||:||:.:|.||:::.|||.:..:|||||||||||||||
 Frog   319 SLKKLKDIVYPNVEESHWLSSLESTHWLEHIKLVLTGAIQVADKVASGKSSVVVHCSDGWDRTAQ 383

  Fly   407 LTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVS 471
            ||:|:||:||.:|||:.|||||::|||:||||||..||||||..|:||||||:||||||.|||:|
 Frog   384 LTSLAMLMLDSYYRTIVGFEVLVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQFIDCVWQMS 448

  Fly   472 QQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLF 536
            :||..|||||||||||::||||||||||||.|.|..|..|.::.||.|||:.|:|...:|.||.
 Frog   449 KQFPTAFEFNEHFLITVLDHLYSCRFGTFLYNCENIRDKEKVREKTQSLWSLISSEKSKYTNPF- 512

  Fly   537 PSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGC--QRTRELLSKQDQLFKLVNELRL 599
              :|.....||.|:||:|.:.||...|.||||.:...|...  ||..|||:.:|...:.:.||::
 Frog   513 --YTKELNRVLYPVASMRHLELWVNYYIRWNPRIRQQQPNPVEQRYMELLALRDDYVRRLEELQI 575

  Fly   600 KSNNRSNSMQTTTRLASP 617
            .::.:.||  :||..:||
 Frog   576 TNSPKMNS--STTSPSSP 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_523489.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	59/101 (58%)
		Myotub-related	184..509	CDD:461958	206/324 (64%)
mtm1	NP_001015828.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		9/26 (35%)
		PH-like	43..142	CDD:473070	59/102 (58%)
		Myotub-related	159..482	CDD:461958	206/328 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..602		6/20 (30%)