Protein Alignment mtm and Mtmr1

DIOPT Version :9

• Sequence 1: NP_001285651.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_036017901.1
• Gene: Mtmr1 / 53332
• MGIID: 1858271
• Length: 704
• Species: Mus musculus
• Alignment Length: 646
• Identity: 324/646 - (50%)
• Similarity: 444/646 - (68%)
• Gaps: 47/646 - (7%)

  Fly     4 SASLADKLASKTASSN--------------SLDSSSKSSSLGSKHGG------GENGILRD-TPF 47
            :|:::.:::....|.|              ::..:.:...|..:|.|      .:...||| ...
Mouse    67 AATISSQISGSVTSENVSRDYKVFRRPDTRNIHKARQRLELEEEHNGYPSEAEADQVALRDGNKL 131

  Fly    48 GYLE------GEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVI 106
            ..:|      ||..:....||.|:||:.|.|.|.||:|::::||:::   :::|..|:|||||||
Mouse   132 AQMEEAPLFPGESIKAIVKDVIYICPFMGAVSGTLTVTDFKMYFKNV---ERDPHFVLDVPLGVI 193

  Fly   107 ARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAH 171
            :||||| ||.|.|:||.||||.||||||||.|:||:...:..:||.|..:|||||....||||.:
Mouse   194 SRVEKI-GAQSHGDNSCGIEIVCKDMRNLRLAYKQEEQRKLGIFENLNKHAFPLSNGQVLFAFNY 257

  Fly   172 AAANSVNGNGGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLR 236
            .....||      ||.||:|::|.:|.|:||:.|:.:|:|.:|..||:|||:..||.:..||.|.
Mouse   258 KEKFPVN------GWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLS 316

  Fly   237 RVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDA 301
            :||.||::.|:|||||::|.:|||||||||||||.:.||..:||.||..||:|||||.||||.||
Mouse   317 KVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLTIFDA 381

  Fly   302 RPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNT 366
            |.::.|..|||||||||:|.||.|.|:.||:|||||||||||||:||..:|:.|:|.|.:.:|.|
Mouse   382 RQNSVADTNKAKGGGYENESAYPNAELIFLEIHNIHVMRESLRKLKEIVYPSIDESHWLSNVDGT 446

  Fly   367 LWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEK 431
            .||::||.:|||||||.||:|:..||||:|||||||||:|||:|:||:||.:|||::|||.||||
Mouse   447 HWLEYIRVLLAGAVRIADKIESGKTSVVIHCSDGWDRTSQLTSLAMLMLDSYYRTIKGFEALIEK 511

  Fly   432 EWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCR 496
            ||:||||:|..|:||||:.|:||||||:||||||.|||:::||.:||||||.|||||:||||||.
Mouse   512 EWISFGHRFALRVGHGDDNHADADRSPIFLQFIDCVWQMTRQFPSAFEFNELFLITILDHLYSCL 576

  Fly   497 FGTFLCNTEAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKG 561
            |||||||.|.:|:.||:...|.|||::|||.||::.||.|.::.:.   ||.|:||:..:.||..
Mouse   577 FGTFLCNCEQQRIKEDVYTNTISLWSYINSQLDEFSNPFFVNYENH---VLYPVASMSHLELWVN 638

  Fly   562 LYCRWNPGLCAPQ---HGCQRTRELLSKQDQLFKLVNELRLKSNNRSNSMQTTTRLASPMH 619
            .|.||||.: .||   |  |..:|||:.:.:|.|.|.:|:.:...|:.| .::.|.:||.|
Mouse   639 YYVRWNPRM-RPQMPIH--QNLKELLAIKAELQKRVEDLQREMATRTIS-SSSERGSSPTH 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_001285651.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	52/101 (51%)
		Myotub-related	184..509	CDD:399535	206/324 (64%)
Mtmr1	XP_036017901.1	PH-GRAM_MTMR1	146..245	CDD:270165	52/102 (51%)
		Myotub-related	262..588	CDD:399535	208/331 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	490	1.000	Domainoid score	I371
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	705	1.000	Inparanoid score	I654
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58725
OrthoDB	1	1.010	-	-		D319276at33208
OrthoFinder	1	1.000	-	-		FOG0000303
OrthoInspector	1	1.000	-	-		otm44050
orthoMCL	1	0.900	-	-		OOG6_101490
Panther	1	1.100	-	-	O	PTHR10807
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X213
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980