Protein Alignment mtm and Sbf

DIOPT Version :10

• Sequence 1: NP_523489.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_477401.2
• Gene: Sbf / 41427
• FlyBaseID: FBgn0025802
• Length: 1993
• Species: Drosophila melanogaster
• Alignment Length: 776
• Identity: 179/776 - (23%)
• Similarity: 277/776 - (35%)
• Gaps: 289/776 - (37%)

  Fly    51 EGEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQ--EPPVVVDVPLGVIARVEKIG 113
            :|.||:.|       |..  |..|||.:||||:.|:..|....  |..:|...|:..:.:.:||.
  Fly   947 DGREDETQ-------CLI--PAEGALFLTNYRVIFKGSPCDPLFCEQVIVRTFPIASLLKEKKIS 1002

  Fly   114 -------------GATSRGEN----------------------------------------SYG- 124
                         |...|..:                                        |||
  Fly  1003 VLYLAHLDQTLTEGLQLRSSSFQLIKVAFDPEVTPEQIESFRKILSKARHPFDEFEYFAFQSYGT 1067

  Fly   125 ----------------IEIFCKD--MRNLR---FAHKQQNHSRRTVFE----------------- 151
                            ::.|.|.  :|..:   |..|||. .|:.|.:
  Fly  1068 MLQGVAPLKTKEKYSTLKGFAKKTLLRGAKKAGFKQKQQT-KRKLVSDYDYGSADAQETQSIDDE 1131

  Fly   152 -------KLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPNDM---WR 206
                   :.|.||.|     ||.....  ...:........|         :|||...:.   :|
  Fly  1132 LEDGDEFETQNNAMP-----RLLTTKD--VERMRERSYVQDW---------KRLGFDAESQRGFR 1180

  Fly   207 ATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQP---- 267
            .:..|.|||.|.||||:...|...||..:..:.:.....|:|:.:|.: ...|.:.|..||
  Fly  1181 ISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRH-ANGALLIRGGQPNSKS 1244

  Fly   268 ----LVGVSGKRNS----------DDEAYLSFI-----------------------MEANAQSD- 294
                |...:|...:          .|:.:|:.|                       :..::.||
  Fly  1245 VIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDD 1309

  Fly   295 --KLTIMDARPSANAI----ANKAKGGGY-------------------------ESEDAYKNVEI 328
              .||...:|...|.:    .||:..||.                         |...|..|:.:
  Fly  1310 RQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNV 1374

  Fly   329 NF------LDIHNIHVMRESLRKVKEACFPT-----TDDSKWQTAIDNTLWLKHIRCI--LAGAV 380
            :|      :|..:|...|.:.:|:..||.|:     .|...:...::.:.||:.|..:  |:|||
  Fly  1375 DFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAV 1439

  Fly   381 RIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIG 445
              ||.::...:||::...||.|.||||::::.|.|||:||::.||.||:|||||:|||:|..|
  Fly  1440 --VDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHR-- 1500

  Fly   446 HGDNKHSDADR----SPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEA 506
             .:.|.|.|:.    :|.||||:|.|.|:.:||..|||||:.:|..:..|..||||.|||.:.|.
  Fly  1501 -SNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCEL 1564

  Fly   507 ER------VAED------LKH--------------------------KTTSLWTHINSSLDQYL- 532
            ||      ..||      .||                          :..:....|..|:..|:
  Fly  1565 ERSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIE 1629

  Fly   533 -----NPLFPSFTHGAE--LVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQRTRELLSK 586
                 .|:|.:|.:..:  :.|||..:|.::.||                 |..|.|.|::
  Fly  1630 RQHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLW-----------------CYYTNEELAQ 1673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_523489.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	34/202 (17%)
		Myotub-related	184..509	CDD:461958	119/423 (28%)
Sbf	NP_477401.2	uDENN	1..91	CDD:214824
		DENN	142..325	CDD:460461
		dDENN	384..452	CDD:129037
		SBF2	584..807	CDD:463536
		PH-GRAM_MTMR5_MTMR13	933..1047	CDD:275396	22/108 (20%)
		PTP-MTMR5-like	1179..1531	CDD:350382	96/357 (27%)
		C1_Sbf-like	1790..1840	CDD:410377
		PH_Sbf1_hMTMR5	1888..1993	CDD:269941