Protein Alignment mtm and Mtmr6

DIOPT Version :9

• Sequence 1: NP_001285651.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_017171460.1
• Gene: Mtmr6 / 219135
• MGIID: 2145637
• Length: 655
• Species: Mus musculus
• Alignment Length: 552
• Identity: 198/552 - (35%)
• Similarity: 288/552 - (52%)
• Gaps: 67/552 - (12%)

  Fly   106 IARVEKIGGATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGR---LF 167
            ||.|||:...||    ...:.|.||:.|.:.|...::..........||     ||...:   |:
Mouse    53 IASVEKLALTTS----GCPLVIQCKNFRIVHFIVPRERDCHDIYNSLLQ-----LSKQAKYEDLY 108

  Fly   168 AFAHAAANSVNGNGGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASD 232
            ||::....  |.....:||.:.:..||..|:||||..|:.:..|..|.:|::||....||:.||.
Mouse   109 AFSYNPKQ--NDTERRNGWQLIDLAAEYERMGVPNANWQLSDANREYKVCETYPRELYVPRTASR 171

  Fly   233 DFLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLT 297
            ..:...:.|||:.||||||:....|:|.|.||||||.|.|. |..:||..|..|.:||..:..:.
Mouse   172 PVIVGSSNFRSKGRLPVLSYCRQGTEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPGNRYMY 235

  Fly   298 IMDARPS--------------------------------------ANAIANKAKGGGYESEDAYK 324
            ::|.||.                                      .|||||:|.|.|||:||.|.
Mouse   236 VVDTRPKHRMQSWWDTQKDIGRIIVRISSKIWNDEKIRESDERKRLNAIANRAAGKGYENEDNYS 300

  Fly   325 NVEINFLDIHNIHVMRESLRKVKEACFPTTDDSK------WQTAIDNTLWLKHIRCILAGAVRIV 383
            |:...|:.|.||||||.||:|:.|     .:.||      :.:.::::.||:||:.:|..|:.:.
Mouse   301 NIRFQFVGIENIHVMRSSLQKLLE-----VNGSKGLSVNDFYSGLESSGWLRHIKAVLDAAIFLA 360

  Fly   384 DKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGD 448
            ..:...:.||:||||||||||:|:.:|..||||.:|||::||.|||||:|:||||||.:|.||.|
Mouse   361 KAIVVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTMKGFMVLIEKDWISFGHKFSERCGHLD 425

  Fly   449 NKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDL 513
            ....:.  ||||.||::.||.::|||..||||||.||:.|.:|::||:||.||.|.:.||....|
Mouse   426 GDPREV--SPVFTQFLECVWHLTQQFPQAFEFNEAFLLQIHEHIHSCQFGNFLGNCQKEREELRL 488

  Fly   514 KHKTTSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQ 578
            |.||.|||..:.....:|||||:.|.:... .||.|..:..:.:.|:.:|.:::..|...|....
Mouse   489 KEKTYSLWPFLLDDKKKYLNPLYSSKSQRL-TVLEPNTASFNFKFWRNMYHQFDRTLHPRQSVLS 552

  Fly   579 RTRELLSKQDQLFKLVNELRLKSNNRSNSMQT 610
            ....:..:..||.:.:.:|..|.....|.:.|
Mouse   553 IIMNMNEQSKQLEEDIKDLEAKIKQCKNGILT 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_001285651.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	14/52 (27%)
		Myotub-related	184..509	CDD:399535	151/368 (41%)
Mtmr6	XP_017171460.1	PH-GRAM_MTMR6	1..101	CDD:270151	16/56 (29%)
		PTP_DSP_cys	130..469	CDD:391942	141/346 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846011
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D824298at2759
OrthoFinder	1	1.000	-	-		FOG0000303
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1956
SonicParanoid	1	1.000	-	-		X213
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.880