Protein Alignment mtm and Mtmr9

DIOPT Version :10

• Sequence 1: NP_523489.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_808262.1
• Gene: Mtmr9 / 210376
• MGIID: 2442842
• Length: 545
• Species: Mus musculus
• Alignment Length: 539
• Identity: 181/539 - (33%)
• Similarity: 268/539 - (49%)
• Gaps: 32/539 - (5%)

  Fly    67 PYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGGATSRGENSYG-IEIFCK 130
            |:...|.|.|.:|.:.|...|.....:|        |.::.  ..|.....|...|.| |.|.||
Mouse    20 PFYTAVEGTLCLTGHHLILSSRQDNTEE--------LWLLH--SNIDAIDKRFVGSLGTIIIKCK 74

  Fly   131 DMR--NLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLA 193
            |.|  .|.....::..:..:..|.|..    |.....::.|.:.....|..    |||..:.|..
Mouse    75 DFRIIQLDIPGMEECLNIASSIEALST----LDSVTLMYPFFYRPMFEVIE----DGWHSFLPEQ 131

  Fly   194 ELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQ 258
            |..........||.:.:|:.::||.|||....|||:..|:.||:||.||...|.||||:.:.:..
Mouse   132 EFEFYSSATSEWRLSYINKDFSICPSYPPTVIVPKSVDDEALRKVAAFRHGGRFPVLSYYHKKNG 196

  Fly   259 ATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAY 323
            ..|.|..|||.|.:|:|..:||..::..:.|..:.   .::|.|....|...:|||||:|.|..|
Mouse   197 MVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRG---YLIDTRSLNVAQQARAKGGGFEQEAHY 258

  Fly   324 KNVEINFLDIHNIHVMRESLRKVKEACFPTTDD-SKWQTAIDNTLWLKHIRCILAGAVRIVDKVE 387
            .........|...||::|||.|:.|||...|.: .:|...::.:.||.||:.||..|......::
Mouse   259 PQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCID 323

  Fly   388 TMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHS 452
            ....||::|.::|.|.|.|:|:|:.::|:|..||:||||.|||:|||..||.||||........|
Mouse   324 REGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSS 388

  Fly   453 DAD-RSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHK 516
            ... .:||||.|:|.|||:.:||..:|||||||||.:.:|.|:.:|||||.|.|:||....|:.|
Mouse   389 KQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFEHAYASQFGTFLGNNESERCKLKLQQK 453

  Fly   517 TTSLWTHIN--SSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGCQR 579
            |.|||:.:|  ..|.::.||||    ....||:.|..:.:|::||:|::.||:..........:.
Mouse   454 TMSLWSWVNRPGELSKFTNPLF----EANNLVIWPSVAPQSLQLWEGIFLRWSRSSKYLDEAYEE 514

  Fly   580 TRELLSKQDQLFKLVNELR 598
            ...::....:|...||.||
Mouse   515 MVNIIEYNKELQAKVNVLR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_523489.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	22/94 (23%)
		Myotub-related	184..509	CDD:461958	129/326 (40%)
Mtmr9	NP_808262.1	PH-GRAM_MTMR9	1..97	CDD:275398	20/86 (23%)
		Myotub-related	121..446	CDD:461958	129/331 (39%)