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Protein Alignment mtm and Mtmr11

DIOPT Version :10

Sequence 1:	NP_523489.1	Gene:	mtm / 33845	FlyBaseID:	FBgn0025742	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_852074.2	Gene:	Mtmr11 / 194126	MGIID:	2652817	Length:	700	Species:	Mus musculus

Alignment Length:	629	Identity:	165/629 - (26%)
Similarity:	246/629 - (39%)	Gaps:	167/629 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSNSLDSSSKSSSLGSKHGGGENGILRDTPFGYLEGEEDQDQKNDVTYVCPYRGP---VFGALTI 78
            ||:.|.|...|..|..:|      ||...|     |..              :||   :.|.|..
Mouse    38 SSHQLGSCLASGCLPGEH------ILAWAP-----GRR--------------KGPGLDLPGTLIC 77

  Fly    79 TNYRLYFRSLPL---RDQEPPVVV--DVPLGVIARVEKIGGATSRGENSYGIEIFCKDMRNLRF- 137
            ||:|:.|:  |.   |.|:.|:..  |..|..|.|:|.:.| .||.:       ..:....|:|
Mouse    78 TNFRVTFQ--PCGWQRKQDTPLSSENDFALINIGRLEAVSG-LSRVQ-------LLRPGSQLKFI 132

  Fly   138 -----AHKQQNHSRRTVFEK--LQANAFPLSYSGRLFAFAHAAANS----------------VNG 179
                 .|.:.....|..||.  |...||.::     .|...|.|.|                |:|
Mouse   133 PEELLLHGRDFRLLRVGFEAGGLAPQAFQVT-----MAIIQARAQSSQVQQYRGITLSKVGKVSG 192

  Fly   180 N-----------GGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDD 233
            :           ..|:        .|.::.|...  ||.:.:||.:.:..|....:.||....|.
Mouse   193 SRKPPIPLLETLEDWE--------TECKKQGARG--WRVSTVNERFDVATSLSGYFWVPNRILDS 247

  Fly   234 FLRRVAQFRSRCRLPVLSWMNPRTQATITRCSQPLVG--VSGKRNSDDEAYLSFIMEANAQSDKL 296
            .:||......:.|.|.|||.:| ..:.:.||.    |  ::...|.:|...:..:::| ..||.:
Mouse   248 EVRRAFAHFHQGRGPRLSWHHP-GGSDLLRCG----GFYIASDPNKEDIRAVESMLQA-GHSDVV 306

  Fly   297 TI--MDARPSANAIANKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTD--DS 357
            .:  ||..||                         ..||...|:      |::..|.|.:.  :.
Mouse   307 LVETMDEMPS-------------------------LADIQLAHL------KLRALCLPDSSVAED 340

  Fly   358 KWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTV 422
            ||.:|::.|.||.::|..|..|..|...|.:...|||:......|....|::|..|||.|..||:
Mouse   341 KWLSALEGTRWLDYVRSCLRKASDISVLVTSRVRSVVLQELGDRDFNGLLSSLVQLLLAPEARTL 405

  Fly   423 RGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLIT 487
            .||:.|:::||::.||.|..|:  ||...|  :.:|||..|:|..||:.|||...|||:|.||:.
Mouse   406 FGFQSLVQREWVAAGHPFLTRL--GDTGAS--EEAPVFPLFLDCAWQLLQQFPAEFEFSEFFLLA 466

  Fly   488 IVDHLYSCRFGTFLCNTEAERVAEDLKHKT-TSLWTHINSSLDQYLNPLFPSFTHGAELVLRPIA 551
            :.|.:......|||.||..||..:..:..: |.::|      .:|..||..|   .|.|.|
Mouse   467 LHDSIRVPDTLTFLRNTPWERGKKSGQFNSYTQVYT------PEYSQPLAGS---SANLHL---- 518

  Fly   552 SVRSVRLWKGLYCR------WNPGLCAPQHGCQRTRELLSKQDQ 589
               ||..|...|.:      .|||. .|:| |..:|  .|:|.|
Mouse   519 ---SVWDWDLRYSKEQISQFLNPGY-DPEH-CPDSR--FSRQQQ 555

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.