Protein Alignment mtm and Mtm1

DIOPT Version :9

• Sequence 1: NP_001285651.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001157662.1
• Gene: Mtm1 / 17772
• MGIID: 1099452
• Length: 603
• Species: Mus musculus
• Alignment Length: 616
• Identity: 327/616 - (53%)
• Similarity: 437/616 - (70%)
• Gaps: 29/616 - (4%)

  Fly    11 LASKTAS---SNSLDSSS-KSSSLGSKHGGGENGILRDT--PFGYLEGEEDQDQKNDVTYVCPYR 69
            :||.:||   |:||::.| |..|        ::|:.:|.  ....|.||....:| :|.|:||:.
Mouse     1 MASASASKYNSHSLENESIKKVS--------QDGVSQDVSETVPRLPGELLITEK-EVIYICPFN 56

  Fly    70 GPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGGATSRGENSYGIEIFCKDMRN 134
            ||:.|.:.|||||||.|||   :.:..:::|||||||:|:||:||||||||||||::|.|||:||
Mouse    57 GPIKGRVYITNYRLYLRSL---ETDSALILDVPLGVISRIEKMGGATSRGENSYGLDITCKDLRN 118

  Fly   135 LRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGWDGWAVYEPLAELRRLG 199
            ||||.||:.||||.:||.|..:||||:::..||||.:....:|      |||.||.|:.|.||.|
Mouse   119 LRFALKQEGHSRRDMFEILVKHAFPLAHNLPLFAFVNEEKFNV------DGWTVYNPVEEYRRQG 177

  Fly   200 VPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSRCRLPVLSWMNPRTQATITRC 264
            :||..||.:.:|:.|.:|::|||:..||...|||.|||:|.||||.|||||||::|..:..|.||
Mouse   178 LPNHHWRISFINKCYELCETYPALLVVPYRTSDDDLRRIATFRSRNRLPVLSWIHPENKMVIMRC 242

  Fly   265 SQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIANKAKGGGYESEDAYKNVEIN 329
            ||||||:|||||.|||.||..|.|.|.|:.||.|.|||||.||:||||.||||||:|||:|.|::
Mouse   243 SQPLVGMSGKRNKDDEKYLDVIRETNKQTSKLMIYDARPSVNAVANKATGGGYESDDAYQNSELS 307

  Fly   330 FLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRCILAGAVRIVDKVETMSTSVV 394
            ||||||||||||||:|||:..:|..::|.|.:::::|.||:||:.:|.||:::.|:|.:..:||:
Mouse   308 FLDIHNIHVMRESLKKVKDIVYPNIEESHWLSSLESTHWLEHIKLVLTGAIQVADQVSSGKSSVL 372

  Fly   395 VHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHKFQQRIGHGDNKHSDADRSPV 459
            ||||||||||||||:|:||:||..|||:.|||:|::|||:||||||..||||||..|:||||||:
Mouse   373 VHCSDGWDRTAQLTSLAMLMLDSFYRTIEGFEILVQKEWISFGHKFASRIGHGDKNHADADRSPI 437

  Fly   460 FLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNTEAERVAEDLKHKTTSLWTHI 524
            ||||||.|||:|:||..||||||.||||::||||||||||||.|.::.|..:.|..:|.|||:.|
Mouse   438 FLQFIDCVWQMSKQFPTAFEFNEGFLITVLDHLYSCRFGTFLFNCDSARERQKLTERTVSLWSLI 502

  Fly   525 NSSLDQYLNPLFPSFTHGAELVLRPIASVRSVRLWKGLYCRWNPGLCAPQHGC--QRTRELLSKQ 587
            ||:.|::.||.   :|.....||.|:||:|.:.||...|.||||.:...|...  ||..|||:.:
Mouse   503 NSNKDKFKNPF---YTKEINRVLYPVASMRHLELWVNYYIRWNPRVKQQQPNPVEQRYMELLALR 564

  Fly   588 DQLFKLVNELRLKSNNRSNSMQTTTRLASPM 618
            |...|.:.||:|.::.:......:|..:|.|
Mouse   565 DDYIKRLEELQLANSAKLADAPASTSSSSQM 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_001285651.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	60/101 (59%)
		Myotub-related	184..509	CDD:399535	204/324 (63%)
Mtm1	NP_001157662.1	PH-like	44..143	CDD:302622	60/102 (59%)
		Myotub-related	150..483	CDD:284109	209/338 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	490	1.000	Domainoid score	I371
eggNOG	1	0.900	-	-		E1_KOG4471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	705	1.000	Inparanoid score	I654
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D319276at33208
OrthoFinder	1	1.000	-	-		FOG0000303
OrthoInspector	1	1.000	-	-		otm44050
orthoMCL	1	0.900	-	-		OOG6_101490
Panther	1	1.100	-	-	LDO	PTHR10807
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1956
SonicParanoid	1	1.000	-	-		X213
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.900