Protein Alignment mtm and mtm-1

DIOPT Version :10

• Sequence 1: NP_523489.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_491531.2
• Gene: mtm-1 / 172148
• WormBaseID: WBGene00003475
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 238/552 - (43%)
• Similarity: 346/552 - (62%)
• Gaps: 26/552 - (4%)

  Fly    58 QKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGGATS----R 118
            :|| |||..|. |...|.:.||.||:.|.............:|:|||.::|:||:|..|:    |
 Worm    38 EKN-VTYFGPL-GKFPGKIVITRYRMVFLVGDGGKMYEQWKLDIPLGQVSRIEKVGRKTTSVAKR 100

  Fly   119 GENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNGNGGW 183
            |:::||..|:|||.|..||.....:..|:.|.:.|...|||||::..:||..|||.......
 Worm   101 GDDNYGFTIYCKDYRVYRFTCNPASSDRKNVCDSLNRYAFPLSHNLPMFASVHAAETPRLMK--- 162

  Fly   184 DGWAVYEPLAELRRLGVPND-MWRATKLNESYAICDSYPAVWAVPKAASDD---FLRRVAQFRSR 244
            |||.:|....|..|||:||. :|:...:|:.|...::||..:.:|..:.::   |::::.:|||:
 Worm   163 DGWKIYSAEKEYERLGIPNSRLWKEVDINKDYKFSETYPRTFVIPTVSWEEGKPFVKKLGEFRSK 227

  Fly   245 CRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIA 309
            .|:|||||:|..|.|:|:|||||:.|:||||:::||.:|:.||.|||...:|.|:||||:.||..
 Worm   228 ERIPVLSWINQTTLASISRCSQPMTGISGKRSAEDERHLTNIMNANANCRELLILDARPAVNAKL 292

  Fly   310 NKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRC 374
            ||||||||  |:.|.|..:.||:||||||:|:||:::..|..|..|:..:..|:|.:.||.|::.
 Worm   293 NKAKGGGY--EENYVNAPLTFLNIHNIHVVRDSLKRLLAALIPRVDEKGYYKALDESKWLNHVQS 355

  Fly   375 ILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHK 439
            ||.|||:.|..|:|...||::|||||||||||||:|:|:.||.:|||:.||.|||||||.|||||
 Worm   356 ILEGAVKAVFNVDTEKQSVLIHCSDGWDRTAQLTSLAMIQLDSYYRTIEGFIVLIEKEWCSFGHK 420

  Fly   440 FQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNT 504
            |.:||||||:.:||.:|||||:||.|.:||:.:||..||||.:..||.::|.||:||:||||.|:
 Worm   421 FGERIGHGDDNYSDGERSPVFVQFCDCLWQIMRQFPWAFEFTQELLICMLDELYACRYGTFLYNS 485

  Fly   505 EAERVAEDLKHKTT-SLWTHINSSLDQYLNPLFPSFTHG-AELVLRPIASVRSVRLWKGLYCRWN 567
            |..|:.:....:|| |.|:::..:..::.||:   |.|| :..|:....|:..:.:|...|.|.|
 Worm   486 EKIRLKDKKCDETTISFWSYVLENKKKFRNPM---FKHGKSNKVINVNPSLCGLHVWIDYYARSN 547

  Fly   568 PGLCAPQH------GCQRTRELLSKQDQLFKL 593
            |.:..|.|      |.|...|.....|::..|
 Worm   548 PYVVTPNHEDVQQPGAQFVDEKKQLLDEIMAL 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_523489.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	37/104 (36%)
		Myotub-related	184..509	CDD:461958	168/328 (51%)
mtm-1	NP_491531.2	PH-GRAM_MTM-like	36..141	CDD:275407	37/104 (36%)
		Myotub-related	163..489	CDD:461958	168/327 (51%)