Protein Alignment mtm and mtmr2

DIOPT Version :10

• Sequence 1: NP_523489.1
• Gene: mtm / 33845
• FlyBaseID: FBgn0025742
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_002935623.3
• Gene: mtmr2 / 100494494
• XenbaseID: XB-GENE-6044385
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 569
• Identity: 329/569 - (57%)
• Similarity: 427/569 - (75%)
• Gaps: 16/569 - (2%)

  Fly    50 LEGEEDQDQKNDVTYVCPYRGPVFGALTITNYRLYFRSLPLRDQEPPVVVDVPLGVIARVEKIGG 114
            |.||..:|...||||:||:.|...|:.|:||||||||||. ||:.  :|:|.|||:|:|:|||||
 Frog     7 LPGESVKDIAKDVTYICPFSGAYRGSFTVTNYRLYFRSLE-RDRH--LVLDAPLGIISRIEKIGG 68

  Fly   115 ATSRGENSYGIEIFCKDMRNLRFAHKQQNHSRRTVFEKLQANAFPLSYSGRLFAFAHAAANSVNG 179
            |.|||||..||||.||||||:|||:||...:|::|||.|...||||:|...||||.:......|
 Frog    69 AASRGENPNGIEIVCKDMRNIRFAYKQDLRTRKSVFENLVKFAFPLNYGLPLFAFEYKEVFPEN- 132

  Fly   180 NGGWDGWAVYEPLAELRRLGVPNDMWRATKLNESYAICDSYPAVWAVPKAASDDFLRRVAQFRSR 244
                 ||.||:|:.|.||.|:||:.||.|::||.|.:||:|||...||...|||.||::|.||::
 Frog   133 -----GWKVYDPIQEYRRQGIPNESWRITRVNERYELCDTYPACLVVPANISDDELRKIAAFRAQ 192

  Fly   245 CRLPVLSWMNPRTQATITRCSQPLVGVSGKRNSDDEAYLSFIMEANAQSDKLTIMDARPSANAIA 309
            .|:|||||::|.:||.||||||||.||:|||:.:||.||..||:|||||.|:.|.|||||.||:|
 Frog   193 DRIPVLSWIHPESQAAITRCSQPLPGVNGKRSKEDEKYLQSIMDANAQSHKVFIFDARPSVNAVA 257

  Fly   310 NKAKGGGYESEDAYKNVEINFLDIHNIHVMRESLRKVKEACFPTTDDSKWQTAIDNTLWLKHIRC 374
            ||||||||||||||:|.|:.|||||||||||||.||:||..:|:..::.|.:.:::|.||:||:.
 Frog   258 NKAKGGGYESEDAYQNAELVFLDIHNIHVMRESQRKLKEISYPSIQEANWLSNLESTHWLEHIKL 322

  Fly   375 ILAGAVRIVDKVETMSTSVVVHCSDGWDRTAQLTALSMLLLDPHYRTVRGFEVLIEKEWLSFGHK 439
            |||||:||.||||:..||||||||||||||.|||:|:|::||.:|||:||||||:||||:||||:
 Frog   323 ILAGALRIADKVESGKTSVVVHCSDGWDRTPQLTSLAMIMLDGYYRTIRGFEVLVEKEWVSFGHR 387

  Fly   440 FQQRIGHGDNKHSDADRSPVFLQFIDSVWQVSQQFNNAFEFNEHFLITIVDHLYSCRFGTFLCNT 504
            |.||.||||..|:||||||:||||||.|||:::||.|||||||||||.|:||||||.|||||||.
 Frog   388 FYQRTGHGDKNHADADRSPMFLQFIDCVWQMTRQFPNAFEFNEHFLIIILDHLYSCLFGTFLCNC 452

  Fly   505 EAERVAEDLKHKTTSLWTHINSSLDQYLNPLFPSF-THGAELVLRPIASVRSVRLWKGLYCRWNP 568
            |.:::.|.:..::.|||:.|||.|:.::|||:.:: :|    ||.|:.|.|::.||.|.|.||||
 Frog   453 ELQKLKEGVVEESVSLWSFINSQLEDFINPLYVNYSSH----VLYPVTSTRNLELWAGYYIRWNP 513

  Fly   569 GLCAPQHGCQRTRELLSKQDQLFKLVNELRLKSNNRSNSMQTTTRLASP 617
            ....|.....|.:.||:|:.:|.|.:.||:.:.:|||.|  ::.|.:||
 Frog   514 RTRPPGAINSRYKVLLAKRAELQKRLEELQREISNRSTS--SSDRGSSP 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtm	NP_523489.1	PH-GRAM_MTMR2_insect-like	57..159	CDD:270164	61/101 (60%)
		Myotub-related	184..509	CDD:461958	215/324 (66%)
mtmr2	XP_002935623.3	PH-like	1..115	CDD:473070	66/110 (60%)
		Myotub-related	130..455	CDD:461958	216/330 (65%)