DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment H2.0 and vsx2

DIOPT Version :9

Sequence 1:	NP_523488.2	Gene:	H2.0 / 33841	FlyBaseID:	FBgn0001170	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_005158862.1	Gene:	vsx2 / 796163	ZFINID:	ZDB-GENE-001222-1	Length:	393	Species:	Danio rerio

Alignment Length:	230	Identity:	58/230 - (25%)
Similarity:	80/230 - (34%)	Gaps:	86/230 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 QRFLG------KTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQG------------------ 283
            |..||      ..|:..||..|.. |...|:.|..|..|.|.|.|.|
Zfish    49 QEILGLNKEPSSAPRSTLDSFPAG-AHLLASRSMLGPAGVGVGVGMGLIGPGGIPSFYSQPAFLE 112

  Fly   284 ----------------------NASAGSNG-------------------KRKRSWSRAVFSNLQR 307
                                  |.||.|:.                   |||:...|.:|::.|.
Zfish   113 VLSDAQNVHLQPLSRTVGPLEHNQSASSDSDDVSSSERKMSKSSLSQSKKRKKRRHRTIFTSYQL 177

  Fly   308 KGLEIQFQQQKYITKPD---RRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSGQEK---QPS 366
            :.||..|.:..|   ||   |..||.:..|.:.:::|||||||.|||.        :||   :.|
Zfish   178 EELEKAFNEAHY---PDVYAREMLAMKTELPEDRIQVWFQNRRAKWRK--------REKCWGRSS 231

  Fly   367 AVPE---SGGVFKTSTPSGDGTPQEALDYSSDSCS 398
            .:.|   .|.:.:.|.|..:...:.|.|...|||:
Zfish   232 VMAEYGLYGAMVRHSIPLPESILKSAKDGIMDSCA 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
H2.0	NP_523488.2	Homeobox	298..351	CDD:278475	21/55 (38%)
vsx2	XP_005158862.1	Homeobox	170..221	CDD:278475	20/53 (38%)
vsx2	XP_005158862.1	OAR	338..355	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910